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Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner.
Fitzpatrick SF, Fábián Z, Schaible B, Lenihan CR, Schwarzl T, Rodriguez J, Zheng X, Li Z, Tambuwala MM, Higgins DG, O'Meara Y, Slattery C, Manresa MC, Fraisl P, Bruning U, Baes M, Carmeliet P, Doherty G, von Kriegsheim A, Cummins EP, Taylor CT. Fitzpatrick SF, et al. Among authors: lenihan cr. Biochem Biophys Res Commun. 2016 Jun 3;474(3):579-586. doi: 10.1016/j.bbrc.2016.04.085. Epub 2016 Apr 27. Biochem Biophys Res Commun. 2016. PMID: 27130823 Free article.
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function.
Tambuwala MM, Cummins EP, Lenihan CR, Kiss J, Stauch M, Scholz CC, Fraisl P, Lasitschka F, Mollenhauer M, Saunders SP, Maxwell PH, Carmeliet P, Fallon PG, Schneider M, Taylor CT. Tambuwala MM, et al. Among authors: lenihan cr. Gastroenterology. 2010 Dec;139(6):2093-101. doi: 10.1053/j.gastro.2010.06.068. Epub 2010 Jun 30. Gastroenterology. 2010. PMID: 20600011
The impact of hypoxia on cell death pathways.
Lenihan CR, Taylor CT. Lenihan CR, et al. Biochem Soc Trans. 2013 Apr;41(2):657-63. doi: 10.1042/BST20120345. Biochem Soc Trans. 2013. PMID: 23514172 Review.
NF-κB links CO2 sensing to innate immunity and inflammation in mammalian cells.
Cummins EP, Oliver KM, Lenihan CR, Fitzpatrick SF, Bruning U, Scholz CC, Slattery C, Leonard MO, McLoughlin P, Taylor CT. Cummins EP, et al. Among authors: lenihan cr. J Immunol. 2010 Oct 1;185(7):4439-45. doi: 10.4049/jimmunol.1000701. Epub 2010 Sep 3. J Immunol. 2010. PMID: 20817876
42 results