Fraga CA - Search Results

1

Beyond the Selective Inhibition of Histone Deacetylase 6.

Rodrigues DA, Thota S, Fraga CA. Rodrigues DA, et al. Among authors: fraga ca. Mini Rev Med Chem. 2016;16(14):1175-84. doi: 10.2174/1389557516666160428115959. Mini Rev Med Chem. 2016. PMID: 27121714 Review.

2

Selective PGHS-2 inhibitors: a rational approach for treatment of the inflammation.

Rodrigues CR, Veloso MP, Verli H, Fraga CA, Miranda AL, Barreiro EJ. Rodrigues CR, et al. Among authors: fraga ca. Curr Med Chem. 2002 Apr;9(8):849-67. doi: 10.2174/0929867024606786. Curr Med Chem. 2002. PMID: 11966448 Review.

3

Design, synthesis, and pharmacological profile of novel fused pyrazolo[4,3-d]pyridine and pyrazolo[3,4-b][1,8]naphthyridine isosteres: a new class of potent and selective acetylcholinesterase inhibitors.

Barreiro EJ, Camara CA, Verli H, Brazil-Más L, Castro NG, Cintra WM, Aracava Y, Rodrigues CR, Fraga CA. Barreiro EJ, et al. Among authors: fraga ca. J Med Chem. 2003 Mar 27;46(7):1144-52. doi: 10.1021/jm020391n. J Med Chem. 2003. PMID: 12646025

4

A proposed molecular basis for the selective resveratrol inhibition of the PGHS-1 peroxidase activity.

Kümmerle AE, Sperandio da Silva GM, Sant'Anna CM, Barreiro EJ, Fraga CA. Kümmerle AE, et al. Among authors: fraga ca. Bioorg Med Chem. 2005 Nov 1;13(21):5981-5. doi: 10.1016/j.bmc.2005.07.028. Bioorg Med Chem. 2005. PMID: 16099662

5

Medicinal chemistry of N-acylhydrazones: new lead-compounds of analgesic, antiinflammatory and antithrombotic drugs.

Fraga CA, Barreiro EJ. Fraga CA, et al. Curr Med Chem. 2006;13(2):167-98. doi: 10.2174/092986706775197881. Curr Med Chem. 2006. PMID: 16472212

6

Privileged structures: a useful concept for the rational design of new lead drug candidates.

Duarte CD, Barreiro EJ, Fraga CA. Duarte CD, et al. Among authors: fraga ca. Mini Rev Med Chem. 2007 Nov;7(11):1108-19. doi: 10.2174/138955707782331722. Mini Rev Med Chem. 2007. PMID: 18045214 Review.

7

NSAIDs revisited: putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARgamma).

Romeiro NC, Sant'Anna CM, Lima LM, Fraga CA, Barreiro EJ. Romeiro NC, et al. Among authors: fraga ca. Eur J Med Chem. 2008 Sep;43(9):1918-25. doi: 10.1016/j.ejmech.2007.11.031. Epub 2007 Dec 14. Eur J Med Chem. 2008. PMID: 18222570

8

Design, synthesis and analgesic properties of novel conformationally-restricted N-acylhydrazones (NAH).

Kümmerle AE, Vieira MM, Schmitt M, Miranda AL, Fraga CA, Bourguignon JJ, Barreiro EJ. Kümmerle AE, et al. Among authors: fraga ca. Bioorg Med Chem Lett. 2009 Sep 1;19(17):4963-6. doi: 10.1016/j.bmcl.2009.07.075. Epub 2009 Jul 18. Bioorg Med Chem Lett. 2009. PMID: 19646868

9

Structural insights into IKKbeta inhibition by natural products staurosporine and quercetin.

Avila CM, Romeiro NC, Sant'Anna CM, Barreiro EJ, Fraga CA. Avila CM, et al. Among authors: fraga ca. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6907-10. doi: 10.1016/j.bmcl.2009.10.076. Epub 2009 Oct 22. Bioorg Med Chem Lett. 2009. PMID: 19896375

10

Design, synthesis, and pharmacological evaluation of N-acylhydrazones and novel conformationally constrained compounds as selective and potent orally active phosphodiesterase-4 inhibitors.

Kümmerle AE, Schmitt M, Cardozo SV, Lugnier C, Villa P, Lopes AB, Romeiro NC, Justiniano H, Martins MA, Fraga CA, Bourguignon JJ, Barreiro EJ. Kümmerle AE, et al. Among authors: fraga ca. J Med Chem. 2012 Sep 13;55(17):7525-45. doi: 10.1021/jm300514y. Epub 2012 Aug 30. J Med Chem. 2012. PMID: 22891752

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