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Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment Hit.
Gerstenberger BS, Trzupek JD, Tallant C, Fedorov O, Filippakopoulos P, Brennan PE, Fedele V, Martin S, Picaud S, Rogers C, Parikh M, Taylor A, Samas B, O'Mahony A, Berg E, Pallares G, Torrey AD, Treiber DK, Samardjiev IJ, Nasipak BT, Padilla-Benavides T, Wu Q, Imbalzano AN, Nickerson JA, Bunnage ME, Müller S, Knapp S, Owen DR. Gerstenberger BS, et al. Among authors: knapp s. J Med Chem. 2016 May 26;59(10):4800-11. doi: 10.1021/acs.jmedchem.6b00012. Epub 2016 May 3. J Med Chem. 2016. PMID: 27115555 Free PMC article.
Structure and regulation of the human Nek2 centrosomal kinase.
Rellos P, Ivins FJ, Baxter JE, Pike A, Nott TJ, Parkinson DM, Das S, Howell S, Fedorov O, Shen QY, Fry AM, Knapp S, Smerdon SJ. Rellos P, et al. Among authors: knapp s. J Biol Chem. 2007 Mar 2;282(9):6833-42. doi: 10.1074/jbc.M609721200. Epub 2006 Dec 31. J Biol Chem. 2007. PMID: 17197699 Free article.
Structural and functional characterization of the human protein kinase ASK1.
Bunkoczi G, Salah E, Filippakopoulos P, Fedorov O, Müller S, Sobott F, Parker SA, Zhang H, Min W, Turk BE, Knapp S. Bunkoczi G, et al. Among authors: knapp s. Structure. 2007 Oct;15(10):1215-26. doi: 10.1016/j.str.2007.08.011. Structure. 2007. PMID: 17937911 Free PMC article.
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Fedorov O, Marsden B, Pogacic V, Rellos P, Müller S, Bullock AN, Schwaller J, Sundström M, Knapp S. Fedorov O, et al. Among authors: knapp s. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20523-8. doi: 10.1073/pnas.0708800104. Epub 2007 Dec 11. Proc Natl Acad Sci U S A. 2007. PMID: 18077363 Free PMC article.
Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3.
Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Atilla-Gokcumen GE, et al. Among authors: knapp s. Chembiochem. 2008 Dec 15;9(18):2933-6. doi: 10.1002/cbic.200800489. Chembiochem. 2008. PMID: 19035373 Free PMC article. No abstract available.
1,284 results