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Targeting glycosylation as a therapeutic approach.
Dwek RA, Butters TD, Platt FM, Zitzmann N. Dwek RA, et al. Among authors: zitzmann n. Nat Rev Drug Discov. 2002 Jan;1(1):65-75. doi: 10.1038/nrd708. Nat Rev Drug Discov. 2002. PMID: 12119611 Review.
Fragments of bacterial endoglycosidase s and immunoglobulin g reveal subdomains of each that contribute to deglycosylation.
Dixon EV, Claridge JK, Harvey DJ, Baruah K, Yu X, Vesiljevic S, Mattick S, Pritchard LK, Krishna B, Scanlan CN, Schnell JR, Higgins MK, Zitzmann N, Crispin M. Dixon EV, et al. Among authors: zitzmann n. J Biol Chem. 2014 May 16;289(20):13876-89. doi: 10.1074/jbc.M113.532812. Epub 2014 Mar 25. J Biol Chem. 2014. PMID: 24668806 Free PMC article.
Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein.
Behrens AJ, Vasiljevic S, Pritchard LK, Harvey DJ, Andev RS, Krumm SA, Struwe WB, Cupo A, Kumar A, Zitzmann N, Seabright GE, Kramer HB, Spencer DI, Royle L, Lee JH, Klasse PJ, Burton DR, Wilson IA, Ward AB, Sanders RW, Moore JP, Doores KJ, Crispin M. Behrens AJ, et al. Among authors: zitzmann n. Cell Rep. 2016 Mar 22;14(11):2695-706. doi: 10.1016/j.celrep.2016.02.058. Epub 2016 Mar 10. Cell Rep. 2016. PMID: 26972002 Free PMC article.
Iminosugar antivirals: the therapeutic sweet spot.
Alonzi DS, Scott KA, Dwek RA, Zitzmann N. Alonzi DS, et al. Among authors: zitzmann n. Biochem Soc Trans. 2017 Apr 15;45(2):571-582. doi: 10.1042/BST20160182. Biochem Soc Trans. 2017. PMID: 28408497 Free PMC article. Review.
313 results