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Discovery and Mechanism of Highly Efficient Cyclic Cell-Penetrating Peptides.
Biochemistry. 2016 May 10;55(18):2601-12. doi: 10.1021/acs.biochem.6b00226. Epub 2016 Apr 28.
Biochemistry. 2016.
PMID: 27089101
Free PMC article.
Early endosomal escape of a cyclic cell-penetrating peptide allows effective cytosolic cargo delivery.
Qian Z, LaRochelle JR, Jiang B, Lian W, Hard RL, Selner NG, Luechapanichkul R, Barrios AM, Pei D.
Qian Z, et al. Among authors: hard rl.
Biochemistry. 2014 Jun 24;53(24):4034-46. doi: 10.1021/bi5004102. Epub 2014 Jun 11.
Biochemistry. 2014.
PMID: 24896852
Free PMC article.
Item in Clipboard
HDAC6 and Ubp-M BUZ domains recognize specific C-terminal sequences of proteins.
Hard RL, Liu J, Shen J, Zhou P, Pei D.
Hard RL, et al.
Biochemistry. 2010 Dec 21;49(50):10737-46. doi: 10.1021/bi101014s. Epub 2010 Nov 29.
Biochemistry. 2010.
PMID: 21090589
Free PMC article.
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Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.
Zhang Y, Zhang J, Yuan C, Hard RL, Park IH, Li C, Bell C, Pei D.
Zhang Y, et al. Among authors: hard rl.
Biochemistry. 2011 Sep 6;50(35):7637-46. doi: 10.1021/bi200439v. Epub 2011 Aug 9.
Biochemistry. 2011.
PMID: 21800896
Free PMC article.
Item in Clipboard
Distinct ligand specificity of the Tiam1 and Tiam2 PDZ domains.
Shepherd TR, Hard RL, Murray AM, Pei D, Fuentes EJ.
Shepherd TR, et al. Among authors: hard rl.
Biochemistry. 2011 Mar 1;50(8):1296-308. doi: 10.1021/bi1013613. Epub 2011 Feb 4.
Biochemistry. 2011.
PMID: 21192692
Free PMC article.
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Engineering human JMJD2A tudor domains for an improved understanding of histone peptide recognition.
Parkinson J, Hard R, Ainsworth R, Wang W.
Parkinson J, et al.
Proteins. 2023 Jan;91(1):32-46. doi: 10.1002/prot.26408. Epub 2022 Aug 16.
Proteins. 2023.
PMID: 35927178
Free PMC article.
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Deciphering and engineering chromodomain-methyllysine peptide recognition.
Hard R, Li N, He W, Ross B, Mo GCH, Peng Q, Stein RSL, Komives E, Wang Y, Zhang J, Wang W.
Hard R, et al.
Sci Adv. 2018 Nov 7;4(11):eaau1447. doi: 10.1126/sciadv.aau1447. eCollection 2018 Nov.
Sci Adv. 2018.
PMID: 30417094
Free PMC article.
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Engineering a Histone Reader Protein by Combining Directed Evolution, Sequencing, and Neural Network Based Ordinal Regression.
Parkinson J, Hard R, Ainsworth RI, Li N, Wang W.
Parkinson J, et al.
J Chem Inf Model. 2020 Aug 24;60(8):3992-4004. doi: 10.1021/acs.jcim.0c00441. Epub 2020 Aug 5.
J Chem Inf Model. 2020.
PMID: 32786513
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