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A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury.
Delbary-Gossart S, Lee S, Baroni M, Lamarche I, Arnone M, Canolle B, Lin A, Sacramento J, Salegio EA, Castel MN, Delesque-Touchard N, Alam A, Laboudie P, Ferzaz B, Savi P, Herbert JM, Manley GT, Ferguson AR, Bresnahan JC, Bono F, Beattie MS. Delbary-Gossart S, et al. Among authors: ferzaz b. Brain. 2016 Jun;139(Pt 6):1762-82. doi: 10.1093/brain/aww074. Epub 2016 Apr 15. Brain. 2016. PMID: 27084575 Free PMC article.
A novel antagonist of p75NTR reduces peripheral expansion and CNS trafficking of pro-inflammatory monocytes and spares function after traumatic brain injury.
Lee S, Mattingly A, Lin A, Sacramento J, Mannent L, Castel MN, Canolle B, Delbary-Gossart S, Ferzaz B, Morganti JM, Rosi S, Ferguson AR, Manley GT, Bresnahan JC, Beattie MS. Lee S, et al. Among authors: ferzaz b. J Neuroinflammation. 2016 Apr 22;13(1):88. doi: 10.1186/s12974-016-0544-4. J Neuroinflammation. 2016. PMID: 27102880 Free PMC article.
SSR180575 (7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide), a peripheral benzodiazepine receptor ligand, promotes neuronal survival and repair.
Ferzaz B, Brault E, Bourliaud G, Robert JP, Poughon G, Claustre Y, Marguet F, Liere P, Schumacher M, Nowicki JP, Fournier J, Marabout B, Sevrin M, George P, Soubrie P, Benavides J, Scatton B. Ferzaz B, et al. J Pharmacol Exp Ther. 2002 Jun;301(3):1067-78. doi: 10.1124/jpet.301.3.1067. J Pharmacol Exp Ther. 2002. PMID: 12023539
Progesterone synthesis and myelin formation in peripheral nerves.
Schumacher M, Guennoun R, Mercier G, Désarnaud F, Lacor P, Bénavides J, Ferzaz B, Robert F, Baulieu EE. Schumacher M, et al. Among authors: ferzaz b. Brain Res Brain Res Rev. 2001 Nov;37(1-3):343-59. doi: 10.1016/s0165-0173(01)00139-4. Brain Res Brain Res Rev. 2001. PMID: 11744099 Review.
Progesterone synthesis and myelin formation by Schwann cells.
Koenig HL, Schumacher M, Ferzaz B, Thi AN, Ressouches A, Guennoun R, Jung-Testas I, Robel P, Akwa Y, Baulieu EE. Koenig HL, et al. Among authors: ferzaz b. Science. 1995 Jun 9;268(5216):1500-3. doi: 10.1126/science.7770777. Science. 1995. PMID: 7770777