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Synthesis and characterization of a series of chiral alkoxymethyl morpholine analogs as dopamine receptor 4 (D4R) antagonists.
Bioorg Med Chem Lett. 2016 May 15;26(10):2481-2488. doi: 10.1016/j.bmcl.2016.03.102. Epub 2016 Mar 30.
Bioorg Med Chem Lett. 2016.
PMID: 27080176
Free PMC article.
De Novo Synthesis of an l-Lemonose Thioglycoside Donor from d-Threonine.
Huseman ED, Townsend SD.
Huseman ED, et al.
Tetrahedron Lett. 2021 Jun 8;73:153097. doi: 10.1016/j.tetlet.2021.153097. Epub 2021 Apr 22.
Tetrahedron Lett. 2021.
PMID: 34176980
Free PMC article.
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The DARK Side of Total Synthesis: Strategies and Tactics in Psychoactive Drug Production.
Chambers SA, DeSousa JM, Huseman ED, Townsend SD.
Chambers SA, et al. Among authors: huseman ed.
ACS Chem Neurosci. 2018 Oct 17;9(10):2307-2330. doi: 10.1021/acschemneuro.7b00528. Epub 2018 Feb 1.
ACS Chem Neurosci. 2018.
PMID: 29342356
Free PMC article.
Review.
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Synthesis and Cytotoxic Evaluation of Arimetamycin A and Its Daunorubicin and Doxorubicin Hybrids.
Huseman ED, Byl JAW, Chapp SM, Schley ND, Osheroff N, Townsend SD.
Huseman ED, et al.
ACS Cent Sci. 2021 Aug 25;7(8):1327-1337. doi: 10.1021/acscentsci.1c00040. Epub 2021 Jul 22.
ACS Cent Sci. 2021.
PMID: 34471677
Free PMC article.
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Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers.
Huseman ED, Lo A, Fedorova O, Elia JL, Gueble SE, Lin K, Sundaram RK, Oh J, Liu J, Menges F, Rees MG, Ronan MM, Roth JA, Batista VS, Crawford JM, Pyle AM, Bindra RS, Herzon SB.
Huseman ED, et al.
J Am Chem Soc. 2024 May 30. doi: 10.1021/jacs.3c06483. Online ahead of print.
J Am Chem Soc. 2024.
PMID: 38815248
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Mechanism-based design of agents that selectively target drug-resistant glioma.
Lin K, Gueble SE, Sundaram RK, Huseman ED, Bindra RS, Herzon SB.
Lin K, et al. Among authors: huseman ed.
Science. 2022 Jul 29;377(6605):502-511. doi: 10.1126/science.abn7570. Epub 2022 Jul 28.
Science. 2022.
PMID: 35901163
Free PMC article.
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Luteolin Decreases Epidermal Growth Factor Receptor-Mediated Cell Proliferation and Induces Apoptosis in Glioblastoma Cell Lines.
Anson DM, Wilcox RM, Huseman ED, Stump TA, Paris RL, Darkwah BO, Lin S, Adegoke AO, Gryka RJ, Jean-Louis DS, Amos S.
Anson DM, et al. Among authors: huseman ed.
Basic Clin Pharmacol Toxicol. 2018 Dec;123(6):678-686. doi: 10.1111/bcpt.13077. Epub 2018 Jul 31.
Basic Clin Pharmacol Toxicol. 2018.
PMID: 29935053
Free article.
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The antiproliferative and apoptotic effects of apigenin on glioblastoma cells.
Stump TA, Santee BN, Williams LP, Kunze RA, Heinze CE, Huseman ED, Gryka RJ, Simpson DS, Amos S.
Stump TA, et al. Among authors: huseman ed.
J Pharm Pharmacol. 2017 Jul;69(7):907-916. doi: 10.1111/jphp.12718. Epub 2017 Mar 28.
J Pharm Pharmacol. 2017.
PMID: 28349530
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