Guo H - Search Results

1

NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses.

Guo H, König R, Deng M, Riess M, Mo J, Zhang L, Petrucelli A, Yoh SM, Barefoot B, Samo M, Sempowski GD, Zhang A, Colberg-Poley AM, Feng H, Lemon SM, Liu Y, Zhang Y, Wen H, Zhang Z, Damania B, Tsao LC, Wang Q, Su L, Duncan JA, Chanda SK, Ting JP. Guo H, et al. Cell Host Microbe. 2016 Apr 13;19(4):515-528. doi: 10.1016/j.chom.2016.03.001. Cell Host Microbe. 2016. PMID: 27078069 Free PMC article.

2

Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol.

Liu SY, Aliyari R, Chikere K, Li G, Marsden MD, Smith JK, Pernet O, Guo H, Nusbaum R, Zack JA, Freiberg AN, Su L, Lee B, Cheng G. Liu SY, et al. Among authors: guo h. Immunity. 2013 Jan 24;38(1):92-105. doi: 10.1016/j.immuni.2012.11.005. Epub 2012 Dec 27. Immunity. 2013. PMID: 23273844 Free PMC article.

3

HIV-1 infection induces interleukin-1β production via TLR8 protein-dependent and NLRP3 inflammasome mechanisms in human monocytes.

Guo H, Gao J, Taxman DJ, Ting JP, Su L. Guo H, et al. J Biol Chem. 2014 Aug 1;289(31):21716-26. doi: 10.1074/jbc.M114.566620. Epub 2014 Jun 17. J Biol Chem. 2014. PMID: 24939850 Free PMC article.

4

Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized mice.

Li G, Cheng M, Nunoya J, Cheng L, Guo H, Yu H, Liu YJ, Su L, Zhang L. Li G, et al. Among authors: guo h. PLoS Pathog. 2014 Jul 31;10(7):e1004291. doi: 10.1371/journal.ppat.1004291. eCollection 2014 Jul. PLoS Pathog. 2014. PMID: 25077616 Free PMC article.

5

Analysis of human innate immune responses to PRINT fabricated nanoparticles with cross validation using a humanized mouse model.

Robbins GR, Roberts RA, Guo H, Reuter K, Shen T, Sempowski GD, McKinnon KP, Su L, DeSimone JM, Ting JP. Robbins GR, et al. Among authors: guo h. Nanomedicine. 2015 Apr;11(3):589-99. doi: 10.1016/j.nano.2014.11.010. Epub 2015 Jan 14. Nanomedicine. 2015. PMID: 25596079 Free PMC article.

6

Inflammasomes: mechanism of action, role in disease, and therapeutics.

Guo H, Callaway JB, Ting JP. Guo H, et al. Nat Med. 2015 Jul;21(7):677-87. doi: 10.1038/nm.3893. Epub 2015 Jun 29. Nat Med. 2015. PMID: 26121197 Free PMC article. Review.

7

CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo.

Tsao LC, Guo H, Jeffrey J, Hoxie JA, Su L. Tsao LC, et al. Among authors: guo h. Retrovirology. 2016 Mar 29;13:22. doi: 10.1186/s12977-016-0255-z. Retrovirology. 2016. PMID: 27026376 Free PMC article.

8

NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes.

Freeman L, Guo H, David CN, Brickey WJ, Jha S, Ting JP. Freeman L, et al. Among authors: guo h. J Exp Med. 2017 May 1;214(5):1351-1370. doi: 10.1084/jem.20150237. Epub 2017 Apr 12. J Exp Med. 2017. PMID: 28404595 Free PMC article.

9

NLRX1 negatively modulates type I IFN to facilitate KSHV reactivation from latency.

Ma Z, Hopcraft SE, Yang F, Petrucelli A, Guo H, Ting JP, Dittmer DP, Damania B. Ma Z, et al. Among authors: guo h. PLoS Pathog. 2017 May 1;13(5):e1006350. doi: 10.1371/journal.ppat.1006350. eCollection 2017 May. PLoS Pathog. 2017. PMID: 28459883 Free PMC article.

10

NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR.

Feng H, Lenarcic EM, Yamane D, Wauthier E, Mo J, Guo H, McGivern DR, González-López O, Misumi I, Reid LM, Whitmire JK, Ting JP, Duncan JA, Moorman NJ, Lemon SM. Feng H, et al. Among authors: guo h. Nat Immunol. 2017 Dec;18(12):1299-1309. doi: 10.1038/ni.3853. Epub 2017 Oct 2. Nat Immunol. 2017. PMID: 28967880 Free PMC article.

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