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HSV-1 ICP0 dimer domain adopts a novel β-barrel fold.
McCloskey E, Kashipathy M, Cooper A, Gao P, Johnson DK, Battaile KP, Lovell S, Davido DJ. McCloskey E, et al. Among authors: cooper a. Proteins. 2024 Feb 19. doi: 10.1002/prot.26673. Online ahead of print. Proteins. 2024. PMID: 38372168
Crystal structures of the naturally fused CS and cytochrome b5 reductase (b5R) domains of Ncb5or reveal an expanded CS fold, extensive CS-b5R interactions and productive binding of the NAD(P)+ nicotinamide ring.
Benson DR, Lovell S, Mehzabeen N, Galeva N, Cooper A, Gao P, Battaile KP, Zhu H. Benson DR, et al. Among authors: cooper a. Acta Crystallogr D Struct Biol. 2019 Jul 1;75(Pt 7):628-638. doi: 10.1107/S205979831900754X. Epub 2019 Jun 26. Acta Crystallogr D Struct Biol. 2019. PMID: 31282472 Free PMC article.
Structure-guided design of direct-acting antivirals that exploit the gem-dimethyl effect and potently inhibit 3CL proteases of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) and middle east respiratory syndrome coronavirus (MERS-CoV).
Dampalla CS, Miller MJ, Kim Y, Zabiegala A, Nguyen HN, Madden TK, Thurman HA, Machen AJ, Cooper A, Liu L, Battaile KP, Lovell S, Chang KO, Groutas WC. Dampalla CS, et al. Among authors: cooper a. Eur J Med Chem. 2023 Jun 5;254:115376. doi: 10.1016/j.ejmech.2023.115376. Epub 2023 Apr 15. Eur J Med Chem. 2023. PMID: 37080108 Free PMC article.
Porous isoreticular non-metal organic frameworks.
O'Shaughnessy M, Glover J, Hafizi R, Barhi M, Clowes R, Chong SY, Argent SP, Day GM, Cooper AI. O'Shaughnessy M, et al. Among authors: cooper ai. Nature. 2024 May 22. doi: 10.1038/s41586-024-07353-9. Online ahead of print. Nature. 2024. PMID: 38778105
Ablation of Sam50 is associated with fragmentation and alterations in metabolism in murine and human myotubes.
Shao B, Killion M, Oliver A, Vang C, Zeleke F, Neikirk K, Vue Z, Garza-Lopez E, Shao JQ, Mungai M, Lam J, Williams Q, Altamura CT, Whiteside A, Kabugi K, McKenzie J, Ezedimma M, Le H, Koh A, Scudese E, Vang L, Marshall AG, Crabtree A, Tanghal JI, Stephens D, Koh HJ, Jenkins BC, Murray SA, Cooper AT, Williams C, Damo SM, McReynolds MR, Gaddy JA, Wanjalla CN, Beasley HK, Hinton A Jr. Shao B, et al. Among authors: cooper at. J Cell Physiol. 2024 May 21. doi: 10.1002/jcp.31293. Online ahead of print. J Cell Physiol. 2024. PMID: 38770789
3,847 results