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P66Shc signals to age.
Trinei M, Berniakovich I, Beltrami E, Migliaccio E, Fassina A, Pelicci P, Giorgio M. Trinei M, et al. Among authors: pelicci p. Aging (Albany NY). 2009 Jun 5;1(6):503-10. doi: 10.18632/aging.100057. Aging (Albany NY). 2009. PMID: 20157533 Free PMC article. Review.
The p66Shc knocked out mice are short lived under natural condition.
Giorgio M, Berry A, Berniakovich I, Poletaeva I, Trinei M, Stendardo M, Hagopian K, Ramsey JJ, Cortopassi G, Migliaccio E, Nötzli S, Amrein I, Lipp HP, Cirulli F, Pelicci PG. Giorgio M, et al. Among authors: pelicci pg. Aging Cell. 2012 Feb;11(1):162-8. doi: 10.1111/j.1474-9726.2011.00770.x. Epub 2011 Dec 28. Aging Cell. 2012. PMID: 22081964 Free article.
Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging.
Gambino V, De Michele G, Venezia O, Migliaccio P, Dall'Olio V, Bernard L, Minardi SP, Della Fazia MA, Bartoli D, Servillo G, Alcalay M, Luzi L, Giorgio M, Scrable H, Pelicci PG, Migliaccio E. Gambino V, et al. Among authors: pelicci pg. Aging Cell. 2013 Jun;12(3):435-45. doi: 10.1111/acel.12060. Epub 2013 Mar 27. Aging Cell. 2013. PMID: 23448364 Free PMC article.
ΔNp63 promotes IGF1 signalling through IRS1 in squamous cell carcinoma.
Frezza V, Fierro C, Gatti E, Peschiaroli A, Lena AM, Petruzzelli MA, Candi E, Anemona L, Mauriello A, Pelicci PG, Melino G, Bernassola F. Frezza V, et al. Aging (Albany NY). 2018 Dec 28;10(12):4224-4240. doi: 10.18632/aging.101725. Aging (Albany NY). 2018. PMID: 30594912 Free PMC article.
543 results