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Heart rate reduction with ivabradine promotes shear stress-dependent anti-inflammatory mechanisms in arteries.
Luong L, Duckles H, Schenkel T, Mahmoud M, Tremoleda JL, Wylezinska-Arridge M, Ali M, Bowden NP, Villa-Uriol MC, van der Heiden K, Xing R, Gijsen FJ, Wentzel J, Lawrie A, Feng S, Arnold N, Gsell W, Lungu A, Hose R, Spencer T, Halliday I, Ridger V, Evans PC. Luong L, et al. Among authors: lawrie a. Thromb Haemost. 2016 Jul 4;116(1):181-90. doi: 10.1160/TH16-03-0214. Epub 2016 Apr 14. Thromb Haemost. 2016. PMID: 27075869 Free article.
Inhibition of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) reverses experimental pulmonary hypertension.
Hameed AG, Arnold ND, Chamberlain J, Pickworth JA, Paiva C, Dawson S, Cross S, Long L, Zhao L, Morrell NW, Crossman DC, Newman CM, Kiely DG, Francis SE, Lawrie A. Hameed AG, et al. Among authors: lawrie a. J Exp Med. 2012 Oct 22;209(11):1919-35. doi: 10.1084/jem.20112716. Epub 2012 Oct 15. J Exp Med. 2012. PMID: 23071256 Free PMC article.
Selective improvement of pulmonary arterial hypertension with a dual ETA/ETB receptors antagonist in the apolipoprotein E-/- model of PAH and atherosclerosis.
Renshall L, Arnold N, West L, Braithwaite A, Pickworth J, Walker R, Alfaidi M, Chamberlain J, Casbolt H, Thompson AAR, Holt C, Iglarz M, Francis S, Lawrie A. Renshall L, et al. Among authors: lawrie a. Pulm Circ. 2018 Jan-Mar;8(1):2045893217752328. doi: 10.1177/2045893217752328. Epub 2017 Dec 20. Pulm Circ. 2018. PMID: 29261014 Free PMC article.
Altered Macrophage Polarization Induces Experimental Pulmonary Hypertension and Is Observed in Patients With Pulmonary Arterial Hypertension.
Zawia A, Arnold ND, West L, Pickworth JA, Turton H, Iremonger J, Braithwaite AT, Cañedo J, Johnston SA, Thompson AAR, Miller G, Lawrie A. Zawia A, et al. Among authors: lawrie a. Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):430-445. doi: 10.1161/ATVBAHA.120.314639. Epub 2020 Nov 5. Arterioscler Thromb Vasc Biol. 2021. PMID: 33147993 Free PMC article.
Zebrafish as a tractable model of human cardiovascular disease.
Bowley G, Kugler E, Wilkinson R, Lawrie A, van Eeden F, Chico TJA, Evans PC, Noël ES, Serbanovic-Canic J. Bowley G, et al. Among authors: lawrie a. Br J Pharmacol. 2022 Mar;179(5):900-917. doi: 10.1111/bph.15473. Epub 2021 May 10. Br J Pharmacol. 2022. PMID: 33788282 Free article. Review.
Pulmonary artery denervation reduces pulmonary artery pressure and induces histological changes in an acute porcine model of pulmonary hypertension.
Rothman AM, Arnold ND, Chang W, Watson O, Swift AJ, Condliffe R, Elliot CA, Kiely DG, Suvarna SK, Gunn J, Lawrie A. Rothman AM, et al. Among authors: lawrie a. Circ Cardiovasc Interv. 2015 Nov;8(11):e002569. doi: 10.1161/CIRCINTERVENTIONS.115.002569. Circ Cardiovasc Interv. 2015. PMID: 26553697 Free PMC article.
Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension.
Boehm M, Arnold N, Braithwaite A, Pickworth J, Lu C, Novoyatleva T, Kiely DG, Grimminger F, Ghofrani HA, Weissmann N, Seeger W, Lawrie A, Schermuly RT, Kojonazarov B. Boehm M, et al. Among authors: lawrie a. BMC Pulm Med. 2018 Mar 2;18(1):41. doi: 10.1186/s12890-018-0604-x. BMC Pulm Med. 2018. PMID: 29499691 Free PMC article.
Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension.
Farkas D, Thompson AAR, Bhagwani AR, Hultman S, Ji H, Kotha N, Farr G, Arnold ND, Braithwaite A, Casbolt H, Cole JE, Sabroe I, Monaco C, Cool CD, Goncharova EA, Lawrie A, Farkas L. Farkas D, et al. Among authors: lawrie a. Am J Respir Crit Care Med. 2019 Jan 15;199(2):199-210. doi: 10.1164/rccm.201707-1370OC. Am J Respir Crit Care Med. 2019. PMID: 30211629 Free PMC article.
365 results