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Heart rate reduction with ivabradine promotes shear stress-dependent anti-inflammatory mechanisms in arteries.
Luong L, Duckles H, Schenkel T, Mahmoud M, Tremoleda JL, Wylezinska-Arridge M, Ali M, Bowden NP, Villa-Uriol MC, van der Heiden K, Xing R, Gijsen FJ, Wentzel J, Lawrie A, Feng S, Arnold N, Gsell W, Lungu A, Hose R, Spencer T, Halliday I, Ridger V, Evans PC. Luong L, et al. Among authors: arnold n. Thromb Haemost. 2016 Jul 4;116(1):181-90. doi: 10.1160/TH16-03-0214. Epub 2016 Apr 14. Thromb Haemost. 2016. PMID: 27075869 Free article.
Altered Macrophage Polarization Induces Experimental Pulmonary Hypertension and Is Observed in Patients With Pulmonary Arterial Hypertension.
Zawia A, Arnold ND, West L, Pickworth JA, Turton H, Iremonger J, Braithwaite AT, Cañedo J, Johnston SA, Thompson AAR, Miller G, Lawrie A. Zawia A, et al. Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):430-445. doi: 10.1161/ATVBAHA.120.314639. Epub 2020 Nov 5. Arterioscler Thromb Vasc Biol. 2021. PMID: 33147993 Free PMC article.
Selective improvement of pulmonary arterial hypertension with a dual ETA/ETB receptors antagonist in the apolipoprotein E-/- model of PAH and atherosclerosis.
Renshall L, Arnold N, West L, Braithwaite A, Pickworth J, Walker R, Alfaidi M, Chamberlain J, Casbolt H, Thompson AAR, Holt C, Iglarz M, Francis S, Lawrie A. Renshall L, et al. Among authors: arnold n. Pulm Circ. 2018 Jan-Mar;8(1):2045893217752328. doi: 10.1177/2045893217752328. Epub 2017 Dec 20. Pulm Circ. 2018. PMID: 29261014 Free PMC article.
A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension.
Arnold ND, Pickworth JA, West LE, Dawson S, Carvalho JA, Casbolt H, Braithwaite AT, Iremonger J, Renshall L, Germaschewski V, McCourt M, Bland-Ward P, Kowash H, Hameed AG, Rothman AMK, Frid MG, Roger Thompson AA, Evans HR, Southwood M, Morrell NW, Crossman DC, Whyte MKB, Stenmark KR, Newman CM, Kiely DG, Francis SE, Lawrie A. Arnold ND, et al. Nat Commun. 2019 Nov 15;10(1):5183. doi: 10.1038/s41467-019-13139-9. Nat Commun. 2019. PMID: 31729368 Free PMC article.
Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension.
Boehm M, Arnold N, Braithwaite A, Pickworth J, Lu C, Novoyatleva T, Kiely DG, Grimminger F, Ghofrani HA, Weissmann N, Seeger W, Lawrie A, Schermuly RT, Kojonazarov B. Boehm M, et al. Among authors: arnold n. BMC Pulm Med. 2018 Mar 2;18(1):41. doi: 10.1186/s12890-018-0604-x. BMC Pulm Med. 2018. PMID: 29499691 Free PMC article.
Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension.
Farkas D, Thompson AAR, Bhagwani AR, Hultman S, Ji H, Kotha N, Farr G, Arnold ND, Braithwaite A, Casbolt H, Cole JE, Sabroe I, Monaco C, Cool CD, Goncharova EA, Lawrie A, Farkas L. Farkas D, et al. Among authors: arnold nd. Am J Respir Crit Care Med. 2019 Jan 15;199(2):199-210. doi: 10.1164/rccm.201707-1370OC. Am J Respir Crit Care Med. 2019. PMID: 30211629 Free PMC article.
566 results