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Enzymatic Macrocyclization of 1,2,3-Triazole Peptide Mimetics.
Oueis E, Jaspars M, Westwood NJ, Naismith JH. Oueis E, et al. Among authors: naismith jh. Angew Chem Int Ed Engl. 2016 May 4;55(19):5842-5. doi: 10.1002/anie.201601564. Epub 2016 Apr 5. Angew Chem Int Ed Engl. 2016. PMID: 27059105 Free PMC article.
The fluorinase from Streptomyces cattleya is also a chlorinase.
Deng H, Cobb SL, McEwan AR, McGlinchey RP, Naismith JH, O'Hagan D, Robinson DA, Spencer JB. Deng H, et al. Among authors: naismith jh. Angew Chem Int Ed Engl. 2006 Jan 23;45(5):759-62. doi: 10.1002/anie.200503582. Angew Chem Int Ed Engl. 2006. PMID: 16370017 Free PMC article. No abstract available.
Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa.
Alphey MS, Pirrie L, Torrie LS, Boulkeroua WA, Gardiner M, Sarkar A, Maringer M, Oehlmann W, Brenk R, Scherman MS, McNeil M, Rejzek M, Field RA, Singh M, Gray D, Westwood NJ, Naismith JH. Alphey MS, et al. Among authors: naismith jh. ACS Chem Biol. 2013 Feb 15;8(2):387-96. doi: 10.1021/cb300426u. Epub 2012 Nov 28. ACS Chem Biol. 2013. PMID: 23138692 Free article.
An enzymatic route to selenazolines.
Koehnke J, Morawitz F, Bent AF, Houssen WE, Shirran SL, Fuszard MA, Smellie IA, Botting CH, Smith MC, Jaspars M, Naismith JH. Koehnke J, et al. Among authors: naismith jh. Chembiochem. 2013 Mar 18;14(5):564-7. doi: 10.1002/cbic.201300037. Epub 2013 Feb 18. Chembiochem. 2013. PMID: 23483642 Free PMC article.
Structure of PatF from Prochloron didemni.
Bent AF, Koehnke J, Houssen WE, Smith MC, Jaspars M, Naismith JH. Bent AF, et al. Among authors: naismith jh. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jun;69(Pt 6):618-23. doi: 10.1107/S1744309113012931. Epub 2013 May 23. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23722837 Free PMC article.
276 results