Gilroy K - Search Results

1

Addiction to Runx1 is partially attenuated by loss of p53 in the Eµ-Myc lymphoma model.

Borland G, Kilbey A, Hay J, Gilroy K, Terry A, Mackay N, Bell M, McDonald A, Mills K, Cameron E, Neil JC. Borland G, et al. Among authors: gilroy k. Oncotarget. 2016 Apr 26;7(17):22973-87. doi: 10.18632/oncotarget.8554. Oncotarget. 2016. PMID: 27056890 Free PMC article.

2

Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis.

Huser CA, Gilroy KL, de Ridder J, Kilbey A, Borland G, Mackay N, Jenkins A, Bell M, Herzyk P, van der Weyden L, Adams DJ, Rust AG, Cameron E, Neil JC. Huser CA, et al. PLoS Genet. 2014 Feb 27;10(2):e1004167. doi: 10.1371/journal.pgen.1004167. eCollection 2014 Feb. PLoS Genet. 2014. PMID: 24586197 Free PMC article.

3

Frequent infection of human cancer xenografts with murine endogenous retroviruses in vivo.

Naseer A, Terry A, Gilroy K, Kilbey A, Watts C, Mackay N, Bell M, Mason S, Blyth K, Cameron E, Neil JC. Naseer A, et al. Among authors: gilroy k. Viruses. 2015 Apr 17;7(4):2014-29. doi: 10.3390/v7042014. Viruses. 2015. PMID: 25912714 Free PMC article.

4

Gamma-Retrovirus Integration Marks Cell Type-Specific Cancer Genes: A Novel Profiling Tool in Cancer Genomics.

Gilroy KL, Terry A, Naseer A, de Ridder J, Allahyar A, Wang W, Carpenter E, Mason A, Wong GK, Cameron ER, Kilbey A, Neil JC. Gilroy KL, et al. PLoS One. 2016 Apr 20;11(4):e0154070. doi: 10.1371/journal.pone.0154070. eCollection 2016. PLoS One. 2016. PMID: 27097319 Free PMC article.

5

The RUNX Genes as Conditional Oncogenes: Insights from Retroviral Targeting and Mouse Models.

Neil JC, Gilroy K, Borland G, Hay J, Terry A, Kilbey A. Neil JC, et al. Among authors: gilroy k. Adv Exp Med Biol. 2017;962:247-264. doi: 10.1007/978-981-10-3233-2_16. Adv Exp Med Biol. 2017. PMID: 28299662 Review.

6

RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins.

Anderson G, Mackay N, Gilroy K, Hay J, Borland G, McDonald A, Bell M, Hassanudin SA, Cameron E, Neil JC, Kilbey A. Anderson G, et al. Among authors: gilroy k. J Cell Biochem. 2018 Mar;119(3):2750-2762. doi: 10.1002/jcb.26443. Epub 2017 Nov 20. J Cell Biochem. 2018. PMID: 29052866 Free PMC article.

7

Collaboration of MYC and RUNX2 in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity.

Hay J, Gilroy K, Huser C, Kilbey A, Mcdonald A, MacCallum A, Holroyd A, Cameron E, Neil JC. Hay J, et al. Among authors: gilroy k. J Cell Biochem. 2019 Oct;120(10):18332-18345. doi: 10.1002/jcb.29143. Epub 2019 Jun 30. J Cell Biochem. 2019. PMID: 31257681 Free PMC article.

8

Disrupting MLV integrase:BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model.

Loyola L, Achuthan V, Gilroy K, Borland G, Kilbey A, Mackay N, Bell M, Hay J, Aiyer S, Fingerman D, Villanueva RA, Cameron E, Kozak CA, Engelman AN, Neil J, Roth MJ. Loyola L, et al. Among authors: gilroy k. PLoS Pathog. 2019 Dec 9;15(12):e1008154. doi: 10.1371/journal.ppat.1008154. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31815961 Free PMC article.

9

β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer.

Suzuki T, Kilbey A, Casa-Rodríguez N, Lawlor A, Georgakopoulou A, Hayman H, Yin Swe KL, Nordin A, Cantù C, Vantourout P, Ridgway RA, Byrne RM, Chen L, Verzi MP, Gay DM, Gil Vázquez E, Belnoue-Davis HL, Gilroy K, Køstner AH, Kersten C, Thuwajit C, Andersen DK, Wiesheu R, Jandke A, Blyth K, Roseweir AK, Leedham SJ, Dunne PD, Edwards J, Hayday A, Sansom OJ, Coffelt SB. Suzuki T, et al. Among authors: gilroy k. Cancer Immunol Res. 2023 Aug 3;11(8):1137-1155. doi: 10.1158/2326-6066.CIR-22-0644. Cancer Immunol Res. 2023. PMID: 37309673 Free PMC article.

10

BRD4-mediated repression of p53 is a target for combination therapy in AML.

Latif AL, Newcombe A, Li S, Gilroy K, Robertson NA, Lei X, Stewart HJS, Cole J, Terradas MT, Rishi L, McGarry L, McKeeve C, Reid C, Clark W, Campos J, Kirschner K, Davis A, Lopez J, Sakamaki JI, Morton JP, Ryan KM, Tait SWG, Abraham SA, Holyoake T, Higgins B, Huang X, Blyth K, Copland M, Chevassut TJT, Keeshan K, Adams PD. Latif AL, et al. Among authors: gilroy k. Nat Commun. 2021 Jan 11;12(1):241. doi: 10.1038/s41467-020-20378-8. Nat Commun. 2021. PMID: 33431824 Free PMC article.

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