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The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization.
Wu MC, Brennan FH, Lynch JP, Mantovani S, Phipps S, Wetsel RA, Ruitenberg MJ, Taylor SM, Woodruff TM. Wu MC, et al. Among authors: ruitenberg mj. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9439-44. doi: 10.1073/pnas.1218815110. Epub 2013 May 21. Proc Natl Acad Sci U S A. 2013. PMID: 23696668 Free PMC article.
PI3Kδ inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model.
Low PC, Manzanero S, Mohannak N, Narayana VK, Nguyen TH, Kvaskoff D, Brennan FH, Ruitenberg MJ, Gelderblom M, Magnus T, Kim HA, Broughton BR, Sobey CG, Vanhaesebroeck B, Stow JL, Arumugam TV, Meunier FA. Low PC, et al. Among authors: ruitenberg mj. Nat Commun. 2014 Mar 14;5:3450. doi: 10.1038/ncomms4450. Nat Commun. 2014. PMID: 24625684 Free article.
Targeting acute inflammation to complement spinal cord repair.
Brennan FH, Ruitenberg MJ. Brennan FH, et al. Among authors: ruitenberg mj. Neural Regen Res. 2015 Oct;10(10):1596-8. doi: 10.4103/1673-5374.165268. Neural Regen Res. 2015. PMID: 26692854 Free PMC article. No abstract available.
IVIg attenuates complement and improves spinal cord injury outcomes in mice.
Brennan FH, Kurniawan ND, Vukovic J, Bartlett PF, Käsermann F, Arumugam TV, Basta M, Ruitenberg MJ. Brennan FH, et al. Among authors: ruitenberg mj. Ann Clin Transl Neurol. 2016 May 25;3(7):495-511. doi: 10.1002/acn3.318. eCollection 2016 Jul. Ann Clin Transl Neurol. 2016. PMID: 27386499 Free PMC article.
84 results