Church WB - Search Results

1

Structure of the PLP-Form of the Human Kynurenine Aminotransferase II in a Novel Spacegroup at 1.83 Å Resolution.

Nematollahi A, Sun G, Harrop SJ, Hanrahan JR, Church WB. Nematollahi A, et al. Among authors: church wb. Int J Mol Sci. 2016 Mar 25;17(4):446. doi: 10.3390/ijms17040446. Int J Mol Sci. 2016. PMID: 27023527 Free PMC article.

2

Design and synthesis of novel inhibitors of human kynurenine aminotransferase-I.

Akladios FN, Nadvi NA, Park J, Hanrahan JR, Kapoor V, Gorrell MD, Church WB. Akladios FN, et al. Among authors: church wb. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1579-81. doi: 10.1016/j.bmcl.2011.12.138. Epub 2012 Jan 10. Bioorg Med Chem Lett. 2012. PMID: 22281190

3

Selective inhibition of human group IIA-secreted phospholipase A2 (hGIIA) signaling reveals arachidonic acid metabolism is associated with colocalization of hGIIA to vimentin in rheumatoid synoviocytes.

Lee LK, Bryant KJ, Bouveret R, Lei PW, Duff AP, Harrop SJ, Huang EP, Harvey RP, Gelb MH, Gray PP, Curmi PM, Cunningham AM, Church WB, Scott KF. Lee LK, et al. Among authors: church wb. J Biol Chem. 2013 May 24;288(21):15269-79. doi: 10.1074/jbc.M112.397893. Epub 2013 Mar 12. J Biol Chem. 2013. PMID: 23482564 Free PMC article. Clinical Trial.

4

Essential structural features of novel antischizophrenic drugs: a review.

Nematollahi A, Aminimoghadamfarouj N, Church WB. Nematollahi A, et al. Among authors: church wb. Med Chem. 2014;10(6):541-9. doi: 10.2174/1573406410666131229150746. Med Chem. 2014. PMID: 24372388 Review.

5

Homology modeling of human kynurenine aminotransferase III and observations on inhibitor binding using molecular docking.

Nematollahi A, Church WB, Nadvi NA, Gorrell MD, Sun G. Nematollahi A, et al. Among authors: church wb. Cent Nerv Syst Agents Med Chem. 2014;14(1):2-9. doi: 10.2174/1871524914666140416095523. Cent Nerv Syst Agents Med Chem. 2014. PMID: 24739074

6

Kynurenine Aminotransferases and the Prospects of Inhibitors for the Treatment of Schizophrenia.

Jayawickrama GS, Sadig RR, Sun G, Nematollahi A, Nadvi NA, Hanrahan JR, Gorrell MD, Church WB. Jayawickrama GS, et al. Among authors: church wb. Curr Med Chem. 2015;22(24):2902-18. doi: 10.2174/0929867322666150608094054. Curr Med Chem. 2015. PMID: 26051411 Review.

7

Expression, purification and crystallization of human kynurenine aminotransferase 2 exploiting a highly optimized codon set.

Sun G, Nematollahi A, Nadvi NA, Kwan AH, Jeffries CM, Church WB. Sun G, et al. Among authors: church wb. Protein Expr Purif. 2016 May;121:41-5. doi: 10.1016/j.pep.2016.01.004. Epub 2016 Jan 8. Protein Expr Purif. 2016. PMID: 26773745

8

Kynurenine Aminotransferase Isozyme Inhibitors: A Review.

Nematollahi A, Sun G, Jayawickrama GS, Church WB. Nematollahi A, et al. Among authors: church wb. Int J Mol Sci. 2016 Jun 15;17(6):946. doi: 10.3390/ijms17060946. Int J Mol Sci. 2016. PMID: 27314340 Free PMC article. Review.

9

Study of the Activity and Possible Mechanism of Action of a Reversible Inhibitor of Recombinant Human KAT-2: A Promising Lead in Neurodegenerative and Cognitive Disorders.

Nematollahi A, Sun G, Jayawickrama GS, Hanrahan JR, Church WB. Nematollahi A, et al. Among authors: church wb. Molecules. 2016 Jun 29;21(7):856. doi: 10.3390/molecules21070856. Molecules. 2016. PMID: 27367665 Free PMC article.

10

Host-Guest Complexes of Carboxylated Pillar[n]arenes With Drugs.

Wheate NJ, Dickson KA, Kim RR, Nematollahi A, Macquart RB, Kayser V, Yu G, Church WB, Marsh DJ. Wheate NJ, et al. Among authors: church wb. J Pharm Sci. 2016 Dec;105(12):3615-3625. doi: 10.1016/j.xphs.2016.09.008. Epub 2016 Oct 21. J Pharm Sci. 2016. PMID: 27776769

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