Brown WL - Search Results

1

APOBEC3G Expression Correlates with T-Cell Infiltration and Improved Clinical Outcomes in High-grade Serous Ovarian Carcinoma.

Leonard B, Starrett GJ, Maurer MJ, Oberg AL, Van Bockstal M, Van Dorpe J, De Wever O, Helleman J, Sieuwerts AM, Berns EM, Martens JW, Anderson BD, Brown WL, Kalli KR, Kaufmann SH, Harris RS. Leonard B, et al. Among authors: brown wl. Clin Cancer Res. 2016 Sep 15;22(18):4746-55. doi: 10.1158/1078-0432.CCR-15-2910. Epub 2016 Mar 25. Clin Cancer Res. 2016. PMID: 27016308 Free PMC article.

2

APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo.

Liddament MT, Brown WL, Schumacher AJ, Harris RS. Liddament MT, et al. Among authors: brown wl. Curr Biol. 2004 Aug 10;14(15):1385-91. doi: 10.1016/j.cub.2004.06.050. Curr Biol. 2004. PMID: 15296757 Free article.

3

Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration.

Mbisa JL, Barr R, Thomas JA, Vandegraaff N, Dorweiler IJ, Svarovskaia ES, Brown WL, Mansky LM, Gorelick RJ, Harris RS, Engelman A, Pathak VK. Mbisa JL, et al. Among authors: brown wl. J Virol. 2007 Jul;81(13):7099-110. doi: 10.1128/JVI.00272-07. Epub 2007 Apr 11. J Virol. 2007. PMID: 17428871 Free PMC article.

4

The DNA deaminase activity of human APOBEC3G is required for Ty1, MusD, and human immunodeficiency virus type 1 restriction.

Schumacher AJ, Haché G, Macduff DA, Brown WL, Harris RS. Schumacher AJ, et al. Among authors: brown wl. J Virol. 2008 Mar;82(6):2652-60. doi: 10.1128/JVI.02391-07. Epub 2008 Jan 9. J Virol. 2008. PMID: 18184715 Free PMC article.

5

Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction.

Refsland EW, Stenglein MD, Shindo K, Albin JS, Brown WL, Harris RS. Refsland EW, et al. Among authors: brown wl. Nucleic Acids Res. 2010 Jul;38(13):4274-84. doi: 10.1093/nar/gkq174. Epub 2010 Mar 22. Nucleic Acids Res. 2010. PMID: 20308164 Free PMC article.

6

The interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombination.

Demorest ZL, MacDuff DA, Brown WL, Morham SG, Parise LV, Harris RS. Demorest ZL, et al. Among authors: brown wl. PLoS One. 2010 Jul 20;5(7):e11660. doi: 10.1371/journal.pone.0011660. PLoS One. 2010. PMID: 20652029 Free PMC article.

7

Long-term restriction by APOBEC3F selects human immunodeficiency virus type 1 variants with restored Vif function.

Albin JS, Haché G, Hultquist JF, Brown WL, Harris RS. Albin JS, et al. Among authors: brown wl. J Virol. 2010 Oct;84(19):10209-19. doi: 10.1128/JVI.00632-10. Epub 2010 Aug 4. J Virol. 2010. PMID: 20686027 Free PMC article.

8

A single amino acid in human APOBEC3F alters susceptibility to HIV-1 Vif.

Albin JS, LaRue RS, Weaver JA, Brown WL, Shindo K, Harjes E, Matsuo H, Harris RS. Albin JS, et al. Among authors: brown wl. J Biol Chem. 2010 Dec 24;285(52):40785-92. doi: 10.1074/jbc.M110.173161. Epub 2010 Oct 22. J Biol Chem. 2010. PMID: 20971849 Free PMC article.

9

Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1.

Hultquist JF, Lengyel JA, Refsland EW, LaRue RS, Lackey L, Brown WL, Harris RS. Hultquist JF, et al. Among authors: brown wl. J Virol. 2011 Nov;85(21):11220-34. doi: 10.1128/JVI.05238-11. Epub 2011 Aug 10. J Virol. 2011. PMID: 21835787 Free PMC article.

10

First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G.

Li M, Shandilya SM, Carpenter MA, Rathore A, Brown WL, Perkins AL, Harki DA, Solberg J, Hook DJ, Pandey KK, Parniak MA, Johnson JR, Krogan NJ, Somasundaran M, Ali A, Schiffer CA, Harris RS. Li M, et al. Among authors: brown wl. ACS Chem Biol. 2012 Mar 16;7(3):506-17. doi: 10.1021/cb200440y. Epub 2012 Jan 17. ACS Chem Biol. 2012. PMID: 22181350 Free PMC article.

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