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Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC.
Al-Qusairi L, Basquin D, Roy A, Stifanelli M, Rajaram RD, Debonneville A, Nita I, Maillard M, Loffing J, Subramanya AR, Staub O. Al-Qusairi L, et al. Among authors: rajaram rd. Am J Physiol Renal Physiol. 2016 Aug 1;311(2):F330-42. doi: 10.1152/ajprenal.00002.2016. Epub 2016 Mar 23. Am J Physiol Renal Physiol. 2016. PMID: 27009335 Free PMC article.
SIRT7 modulates the stability and activity of the renal K-Cl cotransporter KCC4 through deacetylation.
Noriega LG, Melo Z, Rajaram RD, Mercado A, Tovar AR, Velazquez-Villegas LA, Castañeda-Bueno M, Reyes-López Y, Ryu D, Rojas-Vega L, Magaña-Avila G, López-Barradas AM, Sánchez-Hernández M, Debonneville A, Doucet A, Cheval L, Torres N, Auwerx J, Staub O, Gamba G. Noriega LG, et al. Among authors: rajaram rd. EMBO Rep. 2021 May 5;22(5):e50766. doi: 10.15252/embr.202050766. Epub 2021 Mar 22. EMBO Rep. 2021. PMID: 33749979 Free PMC article.
Differential role of nicotinamide adenine dinucleotide deficiency in acute and chronic kidney disease.
Faivre A, Katsyuba E, Verissimo T, Lindenmeyer M, Rajaram RD, Naesens M, Heckenmeyer C, Mottis A, Feraille E, Cippà P, Cohen C, Longchamp A, Allagnat F, Rutkowski JM, Legouis D, Auwerx J, de Seigneux S. Faivre A, et al. Among authors: rajaram rd. Nephrol Dial Transplant. 2021 Jan 1;36(1):60-68. doi: 10.1093/ndt/gfaa124. Nephrol Dial Transplant. 2021. PMID: 33099633
20 results