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Suramin inhibits cullin-RING E3 ubiquitin ligases.
Wu K, Chong RA, Yu Q, Bai J, Spratt DE, Ching K, Lee C, Miao H, Tappin I, Hurwitz J, Zheng N, Shaw GS, Sun Y, Felsenfeld DP, Sanchez R, Zheng JN, Pan ZQ. Wu K, et al. Among authors: zheng jn, zheng n. Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2011-8. doi: 10.1073/pnas.1601089113. Epub 2016 Mar 21. Proc Natl Acad Sci U S A. 2016. PMID: 27001857 Free PMC article.
Structural assembly of cullin-RING ubiquitin ligase complexes.
Zimmerman ES, Schulman BA, Zheng N. Zimmerman ES, et al. Among authors: zheng n. Curr Opin Struct Biol. 2010 Dec;20(6):714-21. doi: 10.1016/j.sbi.2010.08.010. Epub 2010 Sep 27. Curr Opin Struct Biol. 2010. PMID: 20880695 Free PMC article. Review.
Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome.
Lin H, Zhang X, Liu L, Fu Q, Zang C, Ding Y, Su Y, Xu Z, He S, Yang X, Wei X, Mao H, Cui Y, Wei Y, Zhou C, Du L, Huang N, Zheng N, Wang T, Rao F. Lin H, et al. Among authors: zheng n. Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4117-4124. doi: 10.1073/pnas.1911998117. Epub 2020 Feb 11. Proc Natl Acad Sci U S A. 2020. PMID: 32047038 Free PMC article.
Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential.
Wu K, Huynh KQ, Lu I, Moustakim M, Miao H, Yu C, Haeusgen MJ, Hopkins BD, Huang L, Zheng N, Sanchez R, DeVita RJ, Pan ZQ. Wu K, et al. Among authors: zheng n. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2007328118. doi: 10.1073/pnas.2007328118. Proc Natl Acad Sci U S A. 2021. PMID: 33602808 Free PMC article.
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Zheng N, Schulman BA, Song L, Miller JJ, Jeffrey PD, Wang P, Chu C, Koepp DM, Elledge SJ, Pagano M, Conaway RC, Conaway JW, Harper JW, Pavletich NP. Zheng N, et al. Nature. 2002 Apr 18;416(6882):703-9. doi: 10.1038/416703a. Nature. 2002. PMID: 11961546
2,262 results