Sanchez R - Search Results

1

Suramin inhibits cullin-RING E3 ubiquitin ligases.

Wu K, Chong RA, Yu Q, Bai J, Spratt DE, Ching K, Lee C, Miao H, Tappin I, Hurwitz J, Zheng N, Shaw GS, Sun Y, Felsenfeld DP, Sanchez R, Zheng JN, Pan ZQ. Wu K, et al. Among authors: sanchez r. Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2011-8. doi: 10.1073/pnas.1601089113. Epub 2016 Mar 21. Proc Natl Acad Sci U S A. 2016. PMID: 27001857 Free PMC article.

2

Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination.

Chong RA, Wu K, Spratt DE, Yang Y, Lee C, Nayak J, Xu M, Elkholi R, Tappin I, Li J, Hurwitz J, Brown BD, Chipuk JE, Chen ZJ, Sanchez R, Shaw GS, Huang L, Pan ZQ. Chong RA, et al. Among authors: sanchez r. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8434-9. doi: 10.1073/pnas.1407849111. Epub 2014 May 27. Proc Natl Acad Sci U S A. 2014. PMID: 24912152 Free PMC article.

3

Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential.

Wu K, Huynh KQ, Lu I, Moustakim M, Miao H, Yu C, Haeusgen MJ, Hopkins BD, Huang L, Zheng N, Sanchez R, DeVita RJ, Pan ZQ. Wu K, et al. Among authors: sanchez r. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2007328118. doi: 10.1073/pnas.2007328118. Proc Natl Acad Sci U S A. 2021. PMID: 33602808 Free PMC article.

4

Targeting Cullin-RING E3 Ubiquitin Ligase 4 by Small Molecule Modulators.

Wu K, Hopkins BD, Sanchez R, DeVita RJ, Pan ZQ. Wu K, et al. Among authors: sanchez r. J Cell Signal. 2021;2(3):195-205. doi: 10.33696/Signaling.2.051. J Cell Signal. 2021. PMID: 34604860 Free PMC article.

5

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.

Wang P, Alvarez-Perez JC, Felsenfeld DP, Liu H, Sivendran S, Bender A, Kumar A, Sanchez R, Scott DK, Garcia-Ocaña A, Stewart AF. Wang P, et al. Among authors: sanchez r. Nat Med. 2015 Apr;21(4):383-8. doi: 10.1038/nm.3820. Epub 2015 Mar 9. Nat Med. 2015. PMID: 25751815 Free PMC article.

6

Convallatoxin-Induced Reduction of Methionine Import Effectively Inhibits Human Cytomegalovirus Infection and Replication.

Cohen T, Williams JD, Opperman TJ, Sanchez R, Lurain NS, Tortorella D. Cohen T, et al. Among authors: sanchez r. J Virol. 2016 Nov 14;90(23):10715-10727. doi: 10.1128/JVI.01050-16. Print 2016 Dec 1. J Virol. 2016. PMID: 27654292 Free PMC article.

7

The bromodomain: from epigenome reader to druggable target.

Sanchez R, Meslamani J, Zhou MM. Sanchez R, et al. Biochim Biophys Acta. 2014 Aug;1839(8):676-85. doi: 10.1016/j.bbagrm.2014.03.011. Epub 2014 Mar 28. Biochim Biophys Acta. 2014. PMID: 24686119 Free PMC article. Review.

8

Structure-Activity Relationships and Biological Evaluation of 7-Substituted Harmine Analogs for Human β-Cell Proliferation.

Kumar K, Wang P, A Swartz E, Khamrui S, Secor C, B Lazarus M, Sanchez R, F Stewart A, DeVita RJ. Kumar K, et al. Among authors: sanchez r. Molecules. 2020 Apr 23;25(8):1983. doi: 10.3390/molecules25081983. Molecules. 2020. PMID: 32340326 Free PMC article.

9

ChEpiMod: a knowledgebase for chemical modulators of epigenome reader domains.

Meslamani J, Smith SG, Sanchez R, Zhou MM. Meslamani J, et al. Among authors: sanchez r. Bioinformatics. 2014 May 15;30(10):1481-3. doi: 10.1093/bioinformatics/btu052. Epub 2014 Jan 27. Bioinformatics. 2014. PMID: 24470572 Free PMC article.

10

Privileged diazepine compounds and their emergence as bromodomain inhibitors.

Smith SG, Sanchez R, Zhou MM. Smith SG, et al. Among authors: sanchez r. Chem Biol. 2014 May 22;21(5):573-83. doi: 10.1016/j.chembiol.2014.03.004. Epub 2014 Apr 17. Chem Biol. 2014. PMID: 24746559 Free PMC article. Review.

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