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Expression, crystallization and preliminary X-ray crystallographic analysis of glucose-6-phosphate dehydrogenase from the human pathogen Trypanosoma cruzi in complex with substrate.
Ortíz C, Larrieux N, Medeiros A, Botti H, Comini M, Buschiazzo A. Ortíz C, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Nov 1;67(Pt 11):1457-61. doi: 10.1107/S1744309111037821. Epub 2011 Oct 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 22102256 Free PMC article.
Iron-sulfur cluster binding by mitochondrial monothiol glutaredoxin-1 of Trypanosoma brucei: molecular basis of iron-sulfur cluster coordination and relevance for parasite infectivity.
Manta B, Pavan C, Sturlese M, Medeiros A, Crispo M, Berndt C, Krauth-Siegel RL, Bellanda M, Comini MA. Manta B, et al. Among authors: comini ma. Antioxid Redox Signal. 2013 Sep 1;19(7):665-82. doi: 10.1089/ars.2012.4859. Epub 2013 Feb 26. Antioxid Redox Signal. 2013. PMID: 23259530 Free PMC article.
Oxidovanadium(IV) and dioxidovanadium(V) complexes of tridentate salicylaldehyde semicarbazones: searching for prospective antitrypanosomal agents.
Fernández M, Becco L, Correia I, Benítez J, Piro OE, Echeverria GA, Medeiros A, Comini M, Lavaggi ML, González M, Cerecetto H, Moreno V, Pessoa JC, Garat B, Gambino D. Fernández M, et al. J Inorg Biochem. 2013 Oct;127:150-60. doi: 10.1016/j.jinorgbio.2013.02.010. Epub 2013 Mar 4. J Inorg Biochem. 2013. PMID: 23528424
Identification of Novel Chemical Scaffolds Inhibiting Trypanothione Synthetase from Pathogenic Trypanosomatids.
Benítez D, Medeiros A, Fiestas L, Panozzo-Zenere EA, Maiwald F, Prousis KC, Roussaki M, Calogeropoulou T, Detsi A, Jaeger T, Šarlauskas J, Peterlin Mašič L, Kunick C, Labadie GR, Flohé L, Comini MA. Benítez D, et al. Among authors: comini ma. PLoS Negl Trop Dis. 2016 Apr 12;10(4):e0004617. doi: 10.1371/journal.pntd.0004617. eCollection 2016 Apr. PLoS Negl Trop Dis. 2016. PMID: 27070550 Free PMC article.
84 results