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Mitochondrial protein hyperacetylation in the failing heart.
Horton JL, Martin OJ, Lai L, Riley NM, Richards AL, Vega RB, Leone TC, Pagliarini DJ, Muoio DM, Bedi KC Jr, Margulies KB, Coon JJ, Kelly DP. Horton JL, et al. Among authors: vega rb. JCI Insight. 2016 Feb;2(1):e84897. doi: 10.1172/jci.insight.84897. Epub 2016 Feb 25. JCI Insight. 2016. PMID: 26998524 Free PMC article.
The Failing Heart Relies on Ketone Bodies as a Fuel.
Aubert G, Martin OJ, Horton JL, Lai L, Vega RB, Leone TC, Koves T, Gardell SJ, Krüger M, Hoppel CL, Lewandowski ED, Crawford PA, Muoio DM, Kelly DP. Aubert G, et al. Among authors: vega rb. Circulation. 2016 Feb 23;133(8):698-705. doi: 10.1161/CIRCULATIONAHA.115.017355. Epub 2016 Jan 27. Circulation. 2016. PMID: 26819376 Free PMC article.
The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense.
Horton JL, Davidson MT, Kurishima C, Vega RB, Powers JC, Matsuura TR, Petucci C, Lewandowski ED, Crawford PA, Muoio DM, Recchia FA, Kelly DP. Horton JL, et al. Among authors: vega rb. JCI Insight. 2019 Feb 21;4(4):e124079. doi: 10.1172/jci.insight.124079. eCollection 2019 Feb 21. JCI Insight. 2019. PMID: 30668551 Free PMC article.
MondoA drives muscle lipid accumulation and insulin resistance.
Ahn B, Wan S, Jaiswal N, Vega RB, Ayer DE, Titchenell PM, Han X, Won KJ, Kelly DP. Ahn B, et al. Among authors: vega rb. JCI Insight. 2019 Jul 9;5(15):e129119. doi: 10.1172/jci.insight.129119. JCI Insight. 2019. PMID: 31287806 Free PMC article.
Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism.
Gan Z, Rumsey J, Hazen BC, Lai L, Leone TC, Vega RB, Xie H, Conley KE, Auwerx J, Smith SR, Olson EN, Kralli A, Kelly DP. Gan Z, et al. Among authors: vega rb. J Clin Invest. 2013 Jun;123(6):2564-75. doi: 10.1172/JCI67652. Epub 2013 May 8. J Clin Invest. 2013. PMID: 23676496 Free PMC article.
68 results