Leone TC - Search Results

1

Mitochondrial protein hyperacetylation in the failing heart.

Horton JL, Martin OJ, Lai L, Riley NM, Richards AL, Vega RB, Leone TC, Pagliarini DJ, Muoio DM, Bedi KC Jr, Margulies KB, Coon JJ, Kelly DP. Horton JL, et al. Among authors: leone tc. JCI Insight. 2016 Feb;2(1):e84897. doi: 10.1172/jci.insight.84897. Epub 2016 Feb 25. JCI Insight. 2016. PMID: 26998524 Free PMC article.

2

Transcriptional control of a nuclear gene encoding a mitochondrial fatty acid oxidation enzyme in transgenic mice: role for nuclear receptors in cardiac and brown adipose expression.

Disch DL, Rader TA, Cresci S, Leone TC, Barger PM, Vega R, Wood PA, Kelly DP. Disch DL, et al. Among authors: leone tc. Mol Cell Biol. 1996 Aug;16(8):4043-51. doi: 10.1128/MCB.16.8.4043. Mol Cell Biol. 1996. PMID: 8754802 Free PMC article.

3

A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders.

Leone TC, Weinheimer CJ, Kelly DP. Leone TC, et al. Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7473-8. doi: 10.1073/pnas.96.13.7473. Proc Natl Acad Sci U S A. 1999. PMID: 10377439 Free PMC article.

4

Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth.

Barger PM, Brandt JM, Leone TC, Weinheimer CJ, Kelly DP. Barger PM, et al. Among authors: leone tc. J Clin Invest. 2000 Jun;105(12):1723-30. doi: 10.1172/JCI9056. J Clin Invest. 2000. PMID: 10862787 Free PMC article.

5

Effect of endurance training on lipid metabolism in women: a potential role for PPARalpha in the metabolic response to training.

Horowitz JF, Leone TC, Feng W, Kelly DP, Klein S. Horowitz JF, et al. Among authors: leone tc. Am J Physiol Endocrinol Metab. 2000 Aug;279(2):E348-55. doi: 10.1152/ajpendo.2000.279.2.E348. Am J Physiol Endocrinol Metab. 2000. PMID: 10913035 Free article. Clinical Trial.

6

Mitochondrial transcription factor A is increased but expression of ATP synthase beta subunit and medium-chain acyl-CoA dehydrogenase genes are decreased in hearts of copper-deficient rats.

Mao S, Leone TC, Kelly DP, Medeiros DM. Mao S, et al. Among authors: leone tc. J Nutr. 2000 Sep;130(9):2143-50. doi: 10.1093/jn/130.9.2143. J Nutr. 2000. PMID: 10958805

7

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus.

Finck BN, Lehman JJ, Leone TC, Welch MJ, Bennett MJ, Kovacs A, Han X, Gross RW, Kozak R, Lopaschuk GD, Kelly DP. Finck BN, et al. Among authors: leone tc. J Clin Invest. 2002 Jan;109(1):121-30. doi: 10.1172/JCI14080. J Clin Invest. 2002. PMID: 11781357 Free PMC article.

8

Calcineurin and calcium/calmodulin-dependent protein kinase activate distinct metabolic gene regulatory programs in cardiac muscle.

Schaeffer PJ, Wende AR, Magee CJ, Neilson JR, Leone TC, Chen F, Kelly DP. Schaeffer PJ, et al. Among authors: leone tc. J Biol Chem. 2004 Sep 17;279(38):39593-603. doi: 10.1074/jbc.M403649200. Epub 2004 Jul 19. J Biol Chem. 2004. PMID: 15262994 Free article.

9

Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilization.

Luptak I, Balschi JA, Xing Y, Leone TC, Kelly DP, Tian R. Luptak I, et al. Among authors: leone tc. Circulation. 2005 Oct 11;112(15):2339-46. doi: 10.1161/CIRCULATIONAHA.105.534594. Epub 2005 Oct 3. Circulation. 2005. PMID: 16203912

10

The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis.

Lehman JJ, Boudina S, Banke NH, Sambandam N, Han X, Young DM, Leone TC, Gross RW, Lewandowski ED, Abel ED, Kelly DP. Lehman JJ, et al. Among authors: leone tc. Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H185-96. doi: 10.1152/ajpheart.00081.2008. Epub 2008 May 16. Am J Physiol Heart Circ Physiol. 2008. PMID: 18487436 Free PMC article.

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