Lai L - Search Results

1

Mitochondrial protein hyperacetylation in the failing heart.

Horton JL, Martin OJ, Lai L, Riley NM, Richards AL, Vega RB, Leone TC, Pagliarini DJ, Muoio DM, Bedi KC Jr, Margulies KB, Coon JJ, Kelly DP. Horton JL, et al. Among authors: lai l. JCI Insight. 2016 Feb;2(1):e84897. doi: 10.1172/jci.insight.84897. Epub 2016 Feb 25. JCI Insight. 2016. PMID: 26998524 Free PMC article.

2

Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart.

Lai L, Leone TC, Zechner C, Schaeffer PJ, Kelly SM, Flanagan DP, Medeiros DM, Kovacs A, Kelly DP. Lai L, et al. Genes Dev. 2008 Jul 15;22(14):1948-61. doi: 10.1101/gad.1661708. Genes Dev. 2008. PMID: 18628400 Free PMC article.

3

Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity.

Zechner C, Lai L, Zechner JF, Geng T, Yan Z, Rumsey JW, Collia D, Chen Z, Wozniak DF, Leone TC, Kelly DP. Zechner C, et al. Among authors: lai l. Cell Metab. 2010 Dec 1;12(6):633-42. doi: 10.1016/j.cmet.2010.11.008. Cell Metab. 2010. PMID: 21109195 Free PMC article.

4

Toll-like receptor-mediated inflammatory signaling reprograms cardiac energy metabolism by repressing peroxisome proliferator-activated receptor γ coactivator-1 signaling.

Schilling J, Lai L, Sambandam N, Dey CE, Leone TC, Kelly DP. Schilling J, et al. Among authors: lai l. Circ Heart Fail. 2011 Jul;4(4):474-82. doi: 10.1161/CIRCHEARTFAILURE.110.959833. Epub 2011 May 10. Circ Heart Fail. 2011. PMID: 21558447 Free PMC article.

5

Liver-specific PGC-1beta deficiency leads to impaired mitochondrial function and lipogenic response to fasting-refeeding.

Chambers KT, Chen Z, Crawford PA, Fu X, Burgess SC, Lai L, Leone TC, Kelly DP, Finck BN. Chambers KT, et al. Among authors: lai l. PLoS One. 2012;7(12):e52645. doi: 10.1371/journal.pone.0052645. Epub 2012 Dec 28. PLoS One. 2012. PMID: 23285128 Free PMC article.

6

Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism.

Gan Z, Rumsey J, Hazen BC, Lai L, Leone TC, Vega RB, Xie H, Conley KE, Auwerx J, Smith SR, Olson EN, Kralli A, Kelly DP. Gan Z, et al. Among authors: lai l. J Clin Invest. 2013 Jun;123(6):2564-75. doi: 10.1172/JCI67652. Epub 2013 May 8. J Clin Invest. 2013. PMID: 23676496 Free PMC article.

7

PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner.

Chambers KT, Chen Z, Lai L, Leone TC, Towle HC, Kralli A, Crawford PA, Finck BN. Chambers KT, et al. Among authors: lai l. Mol Metab. 2013 May 9;2(3):194-204. doi: 10.1016/j.molmet.2013.05.001. eCollection 2013. Mol Metab. 2013. PMID: 24049734 Free PMC article.

8

A role for peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1) in the regulation of cardiac mitochondrial phospholipid biosynthesis.

Lai L, Wang M, Martin OJ, Leone TC, Vega RB, Han X, Kelly DP. Lai L, et al. J Biol Chem. 2014 Jan 24;289(4):2250-9. doi: 10.1074/jbc.M113.523654. Epub 2013 Dec 11. J Biol Chem. 2014. PMID: 24337569 Free PMC article.

9

A role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growth.

Martin OJ, Lai L, Soundarapandian MM, Leone TC, Zorzano A, Keller MP, Attie AD, Muoio DM, Kelly DP. Martin OJ, et al. Among authors: lai l. Circ Res. 2014 Feb 14;114(4):626-36. doi: 10.1161/CIRCRESAHA.114.302562. Epub 2013 Dec 23. Circ Res. 2014. PMID: 24366168 Free PMC article.

10

Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach.

Lai L, Leone TC, Keller MP, Martin OJ, Broman AT, Nigro J, Kapoor K, Koves TR, Stevens R, Ilkayeva OR, Vega RB, Attie AD, Muoio DM, Kelly DP. Lai L, et al. Circ Heart Fail. 2014 Nov;7(6):1022-31. doi: 10.1161/CIRCHEARTFAILURE.114.001469. Epub 2014 Sep 18. Circ Heart Fail. 2014. PMID: 25236884 Free PMC article.

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