Becq F - Search Results

1

Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis.

Meijer L, Nelson DJ, Riazanski V, Gabdoulkhakova AG, Hery-Arnaud G, Le Berre R, Loaëc N, Oumata N, Galons H, Nowak E, Gueganton L, Dorothée G, Prochazkova M, Hall B, Kulkarni AB, Gray RD, Rossi AG, Witko-Sarsat V, Norez C, Becq F, Ravel D, Mottier D, Rault G. Meijer L, et al. Among authors: becq f. J Innate Immun. 2016;8(4):330-49. doi: 10.1159/000444256. Epub 2016 Mar 18. J Innate Immun. 2016. PMID: 26987072 Free PMC article. Review.

2

General anesthetic octanol and related compounds activate wild-type and delF508 cystic fibrosis chloride channels.

Marcet B, Becq F, Norez C, Delmas P, Verrier B. Marcet B, et al. Among authors: becq f. Br J Pharmacol. 2004 Mar;141(6):905-14. doi: 10.1038/sj.bjp.0705684. Epub 2004 Feb 16. Br J Pharmacol. 2004. PMID: 14967738 Free PMC article.

3

The cystic fibrosis mutation G1349D within the signature motif LSHGH of NBD2 abolishes the activation of CFTR chloride channels by genistein.

Melin P, Thoreau V, Norez C, Bilan F, Kitzis A, Becq F. Melin P, et al. Among authors: becq f. Biochem Pharmacol. 2004 Jun 15;67(12):2187-96. doi: 10.1016/j.bcp.2004.02.022. Biochem Pharmacol. 2004. PMID: 15163550

4

Disruption of CFTR chloride channel alters mechanical properties and cAMP-dependent Cl- transport of mouse aortic smooth muscle cells.

Robert R, Norez C, Becq F. Robert R, et al. Among authors: becq f. J Physiol. 2005 Oct 15;568(Pt 2):483-95. doi: 10.1113/jphysiol.2005.085019. Epub 2005 Aug 4. J Physiol. 2005. PMID: 16081479 Free PMC article.

5

Rescue of DeltaF508-CFTR (cystic fibrosis transmembrane conductance regulator) by curcumin: involvement of the keratin 18 network.

Lipecka J, Norez C, Bensalem N, Baudouin-Legros M, Planelles G, Becq F, Edelman A, Davezac N. Lipecka J, et al. Among authors: becq f. J Pharmacol Exp Ther. 2006 May;317(2):500-5. doi: 10.1124/jpet.105.097667. Epub 2006 Jan 19. J Pharmacol Exp Ther. 2006. PMID: 16424149

6

Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the alpha-glucosidase inhibitor miglustat.

Norez C, Noel S, Wilke M, Bijvelds M, Jorna H, Melin P, DeJonge H, Becq F. Norez C, et al. Among authors: becq f. FEBS Lett. 2006 Apr 3;580(8):2081-6. doi: 10.1016/j.febslet.2006.03.010. Epub 2006 Mar 10. FEBS Lett. 2006. PMID: 16546175 Free article.

7

The glycine residues G551 and G1349 within the ATP-binding cassette signature motifs play critical roles in the activation and inhibition of cystic fibrosis transmembrane conductance regulator channels by phloxine B.

Melin P, Norez C, Callebaut I, Becq F. Melin P, et al. Among authors: becq f. J Membr Biol. 2005 Dec;208(3):203-12. doi: 10.1007/s00232-005-7001-0. Epub 2006 Apr 7. J Membr Biol. 2005. PMID: 16604470

8

Maintaining low Ca2+ level in the endoplasmic reticulum restores abnormal endogenous F508del-CFTR trafficking in airway epithelial cells.

Norez C, Antigny F, Becq F, Vandebrouck C. Norez C, et al. Among authors: becq f. Traffic. 2006 May;7(5):562-73. doi: 10.1111/j.1600-0854.2006.00409.x. Traffic. 2006. PMID: 16643279 Free article.

9

Discovery of pyrrolo[2,3-b]pyrazines derivatives as submicromolar affinity activators of wild type, G551D, and F508del cystic fibrosis transmembrane conductance regulator chloride channels.

Noel S, Faveau C, Norez C, Rogier C, Mettey Y, Becq F. Noel S, et al. Among authors: becq f. J Pharmacol Exp Ther. 2006 Oct;319(1):349-59. doi: 10.1124/jpet.106.104521. Epub 2006 Jul 7. J Pharmacol Exp Ther. 2006. PMID: 16829626

10

Discovery of alpha-aminoazaheterocycle-methylglyoxal adducts as a new class of high-affinity inhibitors of cystic fibrosis transmembrane conductance regulator chloride channels.

Routaboul C, Norez C, Melin P, Molina MC, Boucherle B, Bossard F, Noel S, Robert R, Gauthier C, Becq F, Décout JL. Routaboul C, et al. Among authors: becq f. J Pharmacol Exp Ther. 2007 Sep;322(3):1023-35. doi: 10.1124/jpet.107.123307. Epub 2007 Jun 19. J Pharmacol Exp Ther. 2007. PMID: 17578899

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