Leentjens J - Search Results

1

Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis.

Cheng SC, Scicluna BP, Arts RJ, Gresnigt MS, Lachmandas E, Giamarellos-Bourboulis EJ, Kox M, Manjeri GR, Wagenaars JA, Cremer OL, Leentjens J, van der Meer AJ, van de Veerdonk FL, Bonten MJ, Schultz MJ, Willems PH, Pickkers P, Joosten LA, van der Poll T, Netea MG. Cheng SC, et al. Among authors: leentjens j. Nat Immunol. 2016 Apr;17(4):406-13. doi: 10.1038/ni.3398. Epub 2016 Mar 7. Nat Immunol. 2016. PMID: 26950237

2

Reversal of immunoparalysis in humans in vivo: a double-blind, placebo-controlled, randomized pilot study.

Leentjens J, Kox M, Koch RM, Preijers F, Joosten LA, van der Hoeven JG, Netea MG, Pickkers P. Leentjens J, et al. Am J Respir Crit Care Med. 2012 Nov 1;186(9):838-45. doi: 10.1164/rccm.201204-0645OC. Epub 2012 Jul 19. Am J Respir Crit Care Med. 2012. PMID: 22822024 Clinical Trial.

3

Immunotherapy for the adjunctive treatment of sepsis: from immunosuppression to immunostimulation. Time for a paradigm change?

Leentjens J, Kox M, van der Hoeven JG, Netea MG, Pickkers P. Leentjens J, et al. Am J Respir Crit Care Med. 2013 Jun 15;187(12):1287-93. doi: 10.1164/rccm.201301-0036CP. Am J Respir Crit Care Med. 2013. PMID: 23590272 Review.

4

Modulation of granulocyte kinetics by GM-CSF/IFN-γ in a human LPS rechallenge model.

Kamp VM, Leentjens J, Pillay J, Langereis JD, de Kleijn S, Kox M, Netea MG, Pickkers P, Koenderman L. Kamp VM, et al. Among authors: leentjens j. J Leukoc Biol. 2013 Sep;94(3):513-20. doi: 10.1189/jlb.0213066. Epub 2013 Jun 21. J Leukoc Biol. 2013. PMID: 23794709

5

IFN-γ-stimulated neutrophils suppress lymphocyte proliferation through expression of PD-L1.

de Kleijn S, Langereis JD, Leentjens J, Kox M, Netea MG, Koenderman L, Ferwerda G, Pickkers P, Hermans PW. de Kleijn S, et al. Among authors: leentjens j. PLoS One. 2013 Aug 28;8(8):e72249. doi: 10.1371/journal.pone.0072249. eCollection 2013. PLoS One. 2013. PMID: 24015224 Free PMC article.

6

[Immunomodulation for sepsis: a change of tack?].

Leentjens J, Kox M, Pickkers P. Leentjens J, et al. Ned Tijdschr Geneeskd. 2014;158:A6859. Ned Tijdschr Geneeskd. 2014. PMID: 24518844 Dutch.

7

Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series.

Delsing CE, Gresnigt MS, Leentjens J, Preijers F, Frager FA, Kox M, Monneret G, Venet F, Bleeker-Rovers CP, van de Veerdonk FL, Pickkers P, Pachot A, Kullberg BJ, Netea MG. Delsing CE, et al. Among authors: leentjens j. BMC Infect Dis. 2014 Mar 26;14:166. doi: 10.1186/1471-2334-14-166. BMC Infect Dis. 2014. PMID: 24669841 Free PMC article. Clinical Trial.

8

The effects of orally administered Beta-glucan on innate immune responses in humans, a randomized open-label intervention pilot-study.

Leentjens J, Quintin J, Gerretsen J, Kox M, Pickkers P, Netea MG. Leentjens J, et al. PLoS One. 2014 Sep 30;9(9):e108794. doi: 10.1371/journal.pone.0108794. eCollection 2014. PLoS One. 2014. PMID: 25268806 Free PMC article. Clinical Trial.

9

Gamma-irradiated bacille Calmette-Guérin vaccination does not modulate the innate immune response during experimental human endotoxemia in adult males.

Hamers LA, Kox M, Arts RJ, Blok B, Leentjens J, Netea MG, Pickkers P. Hamers LA, et al. Among authors: leentjens j. J Immunol Res. 2015;2015:261864. doi: 10.1155/2015/261864. Epub 2015 Mar 26. J Immunol Res. 2015. PMID: 25883989 Free PMC article. Clinical Trial.

10

BCG Vaccination Enhances the Immunogenicity of Subsequent Influenza Vaccination in Healthy Volunteers: A Randomized, Placebo-Controlled Pilot Study.

Leentjens J, Kox M, Stokman R, Gerretsen J, Diavatopoulos DA, van Crevel R, Rimmelzwaan GF, Pickkers P, Netea MG. Leentjens J, et al. J Infect Dis. 2015 Dec 15;212(12):1930-8. doi: 10.1093/infdis/jiv332. Epub 2015 Jun 12. J Infect Dis. 2015. PMID: 26071565 Clinical Trial.

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