Al-Mohanna F - Search Results

1

Target β-catenin/CD44/Nanog axis in colon cancer cells by certain N'-(2-oxoindolin-3-ylidene)-2-(benzyloxy)benzohydrazides.

Radwan AA, Al-Mohanna F, Alanazi FK, Manogaran PS, Al-Dhfyan A. Radwan AA, et al. Bioorg Med Chem Lett. 2016 Apr 1;26(7):1664-70. doi: 10.1016/j.bmcl.2016.02.064. Epub 2016 Feb 23. Bioorg Med Chem Lett. 2016. PMID: 26944615

2

Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers.

Ghebeh H, Sleiman GM, Manogaran PS, Al-Mazrou A, Barhoush E, Al-Mohanna FH, Tulbah A, Al-Faqeeh K, Adra CN. Ghebeh H, et al. BMC Cancer. 2013 Jun 14;13:289. doi: 10.1186/1471-2407-13-289. BMC Cancer. 2013. PMID: 23768049 Free PMC article.

3

Fascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathway.

Ghebeh H, Al-Khaldi S, Olabi S, Al-Dhfyan A, Al-Mohanna F, Barnawi R, Tulbah A, Al-Tweigeri T, Ajarim D, Al-Alwan M. Ghebeh H, et al. Br J Cancer. 2014 Oct 14;111(8):1552-61. doi: 10.1038/bjc.2014.453. Epub 2014 Aug 12. Br J Cancer. 2014. PMID: 25117814 Free PMC article.

4

Fascin Is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway.

Barnawi R, Al-Khaldi S, Majed Sleiman G, Sarkar A, Al-Dhfyan A, Al-Mohanna F, Ghebeh H, Al-Alwan M. Barnawi R, et al. Stem Cells. 2016 Dec;34(12):2799-2813. doi: 10.1002/stem.2473. Epub 2016 Aug 21. Stem Cells. 2016. PMID: 27502039

5

PD-L1 promotes OCT4 and Nanog expression in breast cancer stem cells by sustaining PI3K/AKT pathway activation.

Almozyan S, Colak D, Mansour F, Alaiya A, Al-Harazi O, Qattan A, Al-Mohanna F, Al-Alwan M, Ghebeh H. Almozyan S, et al. Int J Cancer. 2017 Oct 1;141(7):1402-1412. doi: 10.1002/ijc.30834. Epub 2017 Jun 30. Int J Cancer. 2017. PMID: 28614911 Free PMC article.

6

β-Catenin Attenuation Inhibits Tumor Growth and Promotes Differentiation in a BRAF^V600E-Driven Thyroid Cancer Animal Model.

Zou M, BinEssa HA, Al-Malki YH, Al-Yahya S, Al-Alwan M, Al-Jammaz I, Khabar KSA, Almohanna F, Assiri AM, Meyer BF, Alzahrani AS, Al-Mohanna FA, Shi Y. Zou M, et al. Mol Cancer Ther. 2021 Sep;20(9):1603-1613. doi: 10.1158/1535-7163.MCT-21-0037. Epub 2021 Jun 17. Mol Cancer Ther. 2021. PMID: 34224366

7

Osteoprotegerin (OPG) mediates the anti-carcinogenic effects of normal breast fibroblasts and targets cancer stem cells through inhibition of the β-catenin pathway.

Alraouji NN, Hendrayani SF, Ghebeh H, Al-Mohanna FH, Aboussekhra A. Alraouji NN, et al. Cancer Lett. 2021 Nov 1;520:374-384. doi: 10.1016/j.canlet.2021.08.013. Epub 2021 Aug 17. Cancer Lett. 2021. PMID: 34416336

8

Crosstalk between aryl hydrocarbon receptor (AhR) and BCL-2 pathways suggests the use of AhR antagonist to maintain normal differentiation state of mammary epithelial cells during BCL-2 inhibition therapy.

Al-Dhfyan A, Alaiya A, Al-Mohanna F, Attwa MW, AlAsmari AF, Bakheet SA, Korashy HM. Al-Dhfyan A, et al. Among authors: al mohanna f. J Adv Res. 2023 Aug;50:177-192. doi: 10.1016/j.jare.2022.10.006. Epub 2022 Oct 26. J Adv Res. 2023. PMID: 36307019 Free PMC article.

9

PD-L1 is overexpressed on breast cancer stem cells through notch3/mTOR axis.

Mansour FA, Al-Mazrou A, Al-Mohanna F, Al-Alwan M, Ghebeh H. Mansour FA, et al. Oncoimmunology. 2020 Mar 3;9(1):1729299. doi: 10.1080/2162402X.2020.1729299. eCollection 2020. Oncoimmunology. 2020. PMID: 32313717 Free PMC article.

10

Tocilizumab potentiates cisplatin cytotoxicity and targets cancer stem cells in triple-negative breast cancer.

Alraouji NN, Al-Mohanna FH, Ghebeh H, Arafah M, Almeer R, Al-Tweigeri T, Aboussekhra A. Alraouji NN, et al. Mol Carcinog. 2020 Sep;59(9):1041-1051. doi: 10.1002/mc.23234. Epub 2020 Jun 14. Mol Carcinog. 2020. PMID: 32537818

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