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Understanding TERT Promoter Mutations: A Common Path to Immortality.
Bell RJ, Rube HT, Xavier-Magalhães A, Costa BM, Mancini A, Song JS, Costello JF. Bell RJ, et al. Among authors: mancini a. Mol Cancer Res. 2016 Apr;14(4):315-23. doi: 10.1158/1541-7786.MCR-16-0003. Epub 2016 Mar 3. Mol Cancer Res. 2016. PMID: 26941407 Free PMC article. Review.
Mutant IDH1 Expression Drives TERT Promoter Reactivation as Part of the Cellular Transformation Process.
Ohba S, Mukherjee J, Johannessen TC, Mancini A, Chow TT, Wood M, Jones L, Mazor T, Marshall RE, Viswanath P, Walsh KM, Perry A, Bell RJ, Phillips JJ, Costello JF, Ronen SM, Pieper RO. Ohba S, et al. Among authors: mancini a. Cancer Res. 2016 Nov 15;76(22):6680-6689. doi: 10.1158/0008-5472.CAN-16-0696. Epub 2016 Oct 6. Cancer Res. 2016. PMID: 27758882 Free PMC article.
Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner.
Mancini A, Xavier-Magalhães A, Woods WS, Nguyen KT, Amen AM, Hayes JL, Fellmann C, Gapinske M, McKinney AM, Hong C, Jones LE, Walsh KM, Bell RJA, Doudna JA, Costa BM, Song JS, Perez-Pinera P, Costello JF. Mancini A, et al. Cancer Cell. 2018 Sep 10;34(3):513-528.e8. doi: 10.1016/j.ccell.2018.08.003. Cancer Cell. 2018. PMID: 30205050 Free PMC article.
Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage.
Amen AM, Fellmann C, Soczek KM, Ren SM, Lew RJ, Knott GJ, Park JE, McKinney AM, Mancini A, Doudna JA, Costello JF. Amen AM, et al. Among authors: mancini a. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2008772118. doi: 10.1073/pnas.2008772118. Proc Natl Acad Sci U S A. 2021. PMID: 33758097 Free PMC article.
1,350 results