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Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction.
Klaus M, Prokoph N, Girbig M, Wang X, Huang YH, Srivastava Y, Hou L, Narasimhan K, Kolatkar PR, Francois M, Jauch R. Klaus M, et al. Among authors: francois m. Nucleic Acids Res. 2016 May 5;44(8):3922-35. doi: 10.1093/nar/gkw130. Epub 2016 Mar 2. Nucleic Acids Res. 2016. PMID: 26939885 Free PMC article.
Sox18 induces development of the lymphatic vasculature in mice.
François M, Caprini A, Hosking B, Orsenigo F, Wilhelm D, Browne C, Paavonen K, Karnezis T, Shayan R, Downes M, Davidson T, Tutt D, Cheah KS, Stacker SA, Muscat GE, Achen MG, Dejana E, Koopman P. François M, et al. Nature. 2008 Dec 4;456(7222):643-7. doi: 10.1038/nature07391. Epub 2008 Oct 19. Nature. 2008. PMID: 18931657
VEGFD regulates blood vascular development by modulating SOX18 activity.
Duong T, Koltowska K, Pichol-Thievend C, Le Guen L, Fontaine F, Smith KA, Truong V, Skoczylas R, Stacker SA, Achen MG, Koopman P, Hogan BM, Francois M. Duong T, et al. Among authors: francois m. Blood. 2014 Feb 13;123(7):1102-12. doi: 10.1182/blood-2013-04-495432. Epub 2013 Nov 22. Blood. 2014. PMID: 24269955 Free article.
Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.
Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, Zuegg J, Robertson AAB, Holmes K, Salim AA, Mamidyala S, Butler MS, Robinson AS, Lesieur E, Johnston W, Alexandrov K, Black BL, Hogan BM, De Val S, Capon RJ, Carroll JS, Bailey TL, Koopman P, Jauch R, Cooper MA, Gambin Y, Francois M. Overman J, et al. Among authors: francois m. Elife. 2017 Jan 31;6:e21221. doi: 10.7554/eLife.21221. Elife. 2017. PMID: 28137359 Free PMC article.
Small-Molecule Inhibitors of the SOX18 Transcription Factor.
Fontaine F, Overman J, Moustaqil M, Mamidyala S, Salim A, Narasimhan K, Prokoph N, Robertson AAB, Lua L, Alexandrov K, Koopman P, Capon RJ, Sierecki E, Gambin Y, Jauch R, Cooper MA, Zuegg J, Francois M. Fontaine F, et al. Among authors: francois m. Cell Chem Biol. 2017 Mar 16;24(3):346-359. doi: 10.1016/j.chembiol.2017.01.003. Epub 2017 Feb 2. Cell Chem Biol. 2017. PMID: 28163017 Free article.
Oncogenic Herpesvirus Engages Endothelial Transcription Factors SOX18 and PROX1 to Increase Viral Genome Copies and Virus Production.
Gramolelli S, Elbasani E, Tuohinto K, Nurminen V, Günther T, Kallinen RE, Kaijalainen SP, Diaz R, Grundhoff A, Haglund C, Ziegelbauer JM, Pellinen T, Bower M, Francois M, Ojala PM. Gramolelli S, et al. Among authors: francois m. Cancer Res. 2020 Aug 1;80(15):3116-3129. doi: 10.1158/0008-5472.CAN-19-3103. Epub 2020 Jun 9. Cancer Res. 2020. PMID: 32518203 Free PMC article.
A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity.
McCann AJ, Lou J, Moustaqil M, Graus MS, Blum A, Fontaine F, Liu H, Luu W, Rudolffi-Soto P, Koopman P, Sierecki E, Gambin Y, Meunier FA, Liu Z, Hinde E, Francois M. McCann AJ, et al. Among authors: francois m. Nucleic Acids Res. 2021 Nov 8;49(19):10931-10955. doi: 10.1093/nar/gkab820. Nucleic Acids Res. 2021. PMID: 34570228 Free PMC article.
783 results