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The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases.
Frandsen KE, Simmons TJ, Dupree P, Poulsen JC, Hemsworth GR, Ciano L, Johnston EM, Tovborg M, Johansen KS, von Freiesleben P, Marmuse L, Fort S, Cottaz S, Driguez H, Henrissat B, Lenfant N, Tuna F, Baldansuren A, Davies GJ, Lo Leggio L, Walton PH. Frandsen KE, et al. Among authors: walton ph. Nat Chem Biol. 2016 Apr;12(4):298-303. doi: 10.1038/nchembio.2029. Epub 2016 Feb 29. Nat Chem Biol. 2016. PMID: 26928935 Free PMC article.
Insights into the oxidative degradation of cellulose by a copper metalloenzyme that exploits biomass components.
Quinlan RJ, Sweeney MD, Lo Leggio L, Otten H, Poulsen JC, Johansen KS, Krogh KB, Jørgensen CI, Tovborg M, Anthonsen A, Tryfona T, Walter CP, Dupree P, Xu F, Davies GJ, Walton PH. Quinlan RJ, et al. Among authors: walton ph. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15079-84. doi: 10.1073/pnas.1105776108. Epub 2011 Aug 29. Proc Natl Acad Sci U S A. 2011. PMID: 21876164 Free PMC article.
The copper active site of CBM33 polysaccharide oxygenases.
Hemsworth GR, Taylor EJ, Kim RQ, Gregory RC, Lewis SJ, Turkenburg JP, Parkin A, Davies GJ, Walton PH. Hemsworth GR, et al. Among authors: walton ph. J Am Chem Soc. 2013 Apr 24;135(16):6069-77. doi: 10.1021/ja402106e. Epub 2013 Apr 10. J Am Chem Soc. 2013. PMID: 23540833 Free PMC article.
Spectroscopic and computational insight into the activation of O2 by the mononuclear Cu center in polysaccharide monooxygenases.
Kjaergaard CH, Qayyum MF, Wong SD, Xu F, Hemsworth GR, Walton DJ, Young NA, Davies GJ, Walton PH, Johansen KS, Hodgson KO, Hedman B, Solomon EI. Kjaergaard CH, et al. Among authors: walton ph, walton dj. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8797-802. doi: 10.1073/pnas.1408115111. Epub 2014 Jun 2. Proc Natl Acad Sci U S A. 2014. PMID: 24889637 Free PMC article.
Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase.
Lo Leggio L, Simmons TJ, Poulsen JC, Frandsen KE, Hemsworth GR, Stringer MA, von Freiesleben P, Tovborg M, Johansen KS, De Maria L, Harris PV, Soong CL, Dupree P, Tryfona T, Lenfant N, Henrissat B, Davies GJ, Walton PH. Lo Leggio L, et al. Among authors: walton ph. Nat Commun. 2015 Jan 22;6:5961. doi: 10.1038/ncomms6961. Nat Commun. 2015. PMID: 25608804 Free PMC article.
Lytic Polysaccharide Monooxygenases in Biomass Conversion.
Hemsworth GR, Johnston EM, Davies GJ, Walton PH. Hemsworth GR, et al. Among authors: walton ph. Trends Biotechnol. 2015 Dec;33(12):747-761. doi: 10.1016/j.tibtech.2015.09.006. Epub 2015 Oct 21. Trends Biotechnol. 2015. PMID: 26472212 Review.
Lignocellulose degradation mechanisms across the Tree of Life.
Cragg SM, Beckham GT, Bruce NC, Bugg TD, Distel DL, Dupree P, Etxabe AG, Goodell BS, Jellison J, McGeehan JE, McQueen-Mason SJ, Schnorr K, Walton PH, Watts JE, Zimmer M. Cragg SM, et al. Among authors: walton ph. Curr Opin Chem Biol. 2015 Dec;29:108-19. doi: 10.1016/j.cbpa.2015.10.018. Epub 2015 Nov 14. Curr Opin Chem Biol. 2015. PMID: 26583519 Free PMC article. Review.
62 results