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N-ω-chloroacetyl-L-ornithine has in-vitro activity against cancer cell lines and in-vivo activity against ascitic and solid tumors.
Vargas-Ramírez AL, Medina-Enríquez MM, Cordero-Rodríguez NI, Ruiz-Cuello T, Aguilar-Faisal L, Trujillo-Ferrara JG, Alcántara-Farfán V, Rodríguez-Páez L. Vargas-Ramírez AL, et al. Among authors: medina enriquez mm. Anticancer Drugs. 2016 Jul;27(6):508-18. doi: 10.1097/CAD.0000000000000353. Anticancer Drugs. 2016. PMID: 26918391
N-ω-chloroacetyl-l-ornithine, a new competitive inhibitor of ornithine decarboxylase, induces selective growth inhibition and cytotoxicity on human cancer cells versus normal cells.
Medina-Enríquez MM, Alcántara-Farfán V, Aguilar-Faisal L, Trujillo-Ferrara JG, Rodríguez-Páez L, Vargas-Ramírez AL. Medina-Enríquez MM, et al. J Enzyme Inhib Med Chem. 2015 Jun;30(3):345-53. doi: 10.3109/14756366.2014.926342. Epub 2014 Jun 18. J Enzyme Inhib Med Chem. 2015. PMID: 24939101
ACE2: the molecular doorway to SARS-CoV-2.
Medina-Enríquez MM, Lopez-León S, Carlos-Escalante JA, Aponte-Torres Z, Cuapio A, Wegman-Ostrosky T. Medina-Enríquez MM, et al. Cell Biosci. 2020 Dec 30;10(1):148. doi: 10.1186/s13578-020-00519-8. Cell Biosci. 2020. PMID: 33380340 Free PMC article. Review.