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Biotransformation of LASSBio-579 and pharmacological evaluation of p-hydroxylated metabolite a N-phenylpiperazine antipsychotic lead compound.
Gomes TF, Pompeu TE, Rodrigues DA, Noël F, Menegatti R, Andrade CH, Sabino JR, Gil ES, Dalla Costa T, Betti AH, Antonio CB, Rates SM, Fraga CA, Barreiro EJ, de Oliveira V. Gomes TF, et al. Among authors: sabino jr. Eur J Med Chem. 2013 Apr;62:214-21. doi: 10.1016/j.ejmech.2012.08.011. Epub 2012 Aug 20. Eur J Med Chem. 2013. PMID: 23353740
LQFM030 reduced Ehrlich ascites tumor cell proliferation and VEGF levels.
da Mota MF, de Carvalho FS, de Ávila RI, de Ávila PHM, Cortez AP, Menegatti R, Sabino JR, Dos Santos TRM, Gomes SA, da Cunha LC, Valadares MC. da Mota MF, et al. Among authors: sabino jr. Life Sci. 2018 May 15;201:1-8. doi: 10.1016/j.lfs.2017.12.029. Epub 2017 Dec 24. Life Sci. 2018. PMID: 29278686
Anti-inflammatory and antinociceptive activity profile of a new lead compound - LQFM219.
Galvão GM, Florentino IF, Sanz G, Vaz BG, Lião LM, Sabino JR, Cardoso CS, da Silva DPB, Costa EA, Silva ALP, da Silva ACG, Valadares MC, Leite JA, de S Gil E, Menegatti R. Galvão GM, et al. Among authors: sabino jr. Int Immunopharmacol. 2020 Nov;88:106893. doi: 10.1016/j.intimp.2020.106893. Epub 2020 Sep 3. Int Immunopharmacol. 2020. PMID: 32892073
33 results