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Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair.
Croglio MP, Haake JM, Ryan CP, Wang VS, Lapier J, Schlarbaum JP, Dayani Y, Artuso E, Prandi C, Koltai H, Agama K, Pommier Y, Chen Y, Tricoli L, LaRocque JR, Albanese C, Yarden RI. Croglio MP, et al. Among authors: tricoli l. Oncotarget. 2016 Mar 22;7(12):13984-4001. doi: 10.18632/oncotarget.7414. Oncotarget. 2016. PMID: 26910887 Free PMC article.
The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells.
Ringer L, Sirajuddin P, Tricoli L, Waye S, Choudhry MU, Parasido E, Sivakumar A, Heckler M, Naeem A, Abdelgawad I, Liu X, Feldman AS, Lee RJ, Wu CL, Yenugonda V, Kallakury B, Dritschilo A, Lynch J, Schlegel R, Rodriguez O, Pestell RG, Avantaggiati ML, Albanese C. Ringer L, et al. Among authors: tricoli l. Oncotarget. 2014 Nov 15;5(21):10678-91. doi: 10.18632/oncotarget.2528. Oncotarget. 2014. PMID: 25296977 Free PMC article.
Characterization of the effects of defined, multidimensional culture conditions on conditionally reprogrammed primary human prostate cells.
Tricoli L, Naeem A, Parasido E, Mikhaiel JP, Choudhry MU, Berry DL, Abdelgawad IA, Lee RJ, Feldman AS, Ihemelandu C, Avantaggiati M, Kumar D, Byers S, Gallagher R, Wulfkuhle J, Petricoin E, Rodriguez O, Albanese C. Tricoli L, et al. Oncotarget. 2017 Dec 18;9(2):2193-2207. doi: 10.18632/oncotarget.23363. eCollection 2018 Jan 5. Oncotarget. 2017. PMID: 29416764 Free PMC article.
Predicting new drug indications for prostate cancer: The integration of an in silico proteochemometric network pharmacology platform with patient-derived primary prostate cells.
Naeem A, Dakshanamurthy S, Walthieu H, Parasido E, Avantaggiati M, Tricoli L, Kumar D, Lee RJ, Feldman A, Noon MS, Byers S, Rodriguez O, Albanese C. Naeem A, et al. Among authors: tricoli l. Prostate. 2020 Oct;80(14):1233-1243. doi: 10.1002/pros.24050. Epub 2020 Aug 6. Prostate. 2020. PMID: 32761925 Free PMC article.
25 results