Brüning JC - Search Results

1

Dicer1-miR-328-Bace1 signalling controls brown adipose tissue differentiation and function.

Oliverio M, Schmidt E, Mauer J, Baitzel C, Hansmeier N, Khani S, Konieczka S, Pradas-Juni M, Brodesser S, Van TM, Bartsch D, Brönneke HS, Heine M, Hilpert H, Tarcitano E, Garinis GA, Frommolt P, Heeren J, Mori MA, Brüning JC, Kornfeld JW. Oliverio M, et al. Among authors: bruning jc. Nat Cell Biol. 2016 Mar;18(3):328-36. doi: 10.1038/ncb3316. Epub 2016 Feb 22. Nat Cell Biol. 2016. PMID: 26900752

2

Enhanced leptin-stimulated Pi3k activation in the CNS promotes white adipose tissue transdifferentiation.

Plum L, Rother E, Münzberg H, Wunderlich FT, Morgan DA, Hampel B, Shanabrough M, Janoschek R, Könner AC, Alber J, Suzuki A, Krone W, Horvath TL, Rahmouni K, Brüning JC. Plum L, et al. Among authors: bruning jc. Cell Metab. 2007 Dec;6(6):431-45. doi: 10.1016/j.cmet.2007.10.012. Cell Metab. 2007. PMID: 18054313 Free article.

3

Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity.

Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LH, van der Horst GT, Brüning JC, Niessen CM, Hoeijmakers JH, Schumacher B. Garinis GA, et al. Among authors: bruning jc. Nat Cell Biol. 2009 May;11(5):604-15. doi: 10.1038/ncb1866. Epub 2009 Apr 12. Nat Cell Biol. 2009. PMID: 19363488 Free PMC article.

4

MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity.

Kleinridders A, Schenten D, Könner AC, Belgardt BF, Mauer J, Okamura T, Wunderlich FT, Medzhitov R, Brüning JC. Kleinridders A, et al. Among authors: bruning jc. Cell Metab. 2009 Oct;10(4):249-59. doi: 10.1016/j.cmet.2009.08.013. Cell Metab. 2009. PMID: 19808018 Free PMC article.

5

Hepatic Bax inhibitor-1 inhibits IRE1alpha and protects from obesity-associated insulin resistance and glucose intolerance.

Bailly-Maitre B, Belgardt BF, Jordan SD, Coornaert B, von Freyend MJ, Kleinridders A, Mauer J, Cuddy M, Kress CL, Willmes D, Essig M, Hampel B, Protzer U, Reed JC, Brüning JC. Bailly-Maitre B, et al. Among authors: bruning jc. J Biol Chem. 2010 Feb 26;285(9):6198-207. doi: 10.1074/jbc.M109.056648. Epub 2009 Dec 7. J Biol Chem. 2010. PMID: 19996103 Free PMC article.

6

Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism.

Belgardt BF, Mauer J, Wunderlich FT, Ernst MB, Pal M, Spohn G, Brönneke HS, Brodesser S, Hampel B, Schauss AC, Brüning JC. Belgardt BF, et al. Among authors: bruning jc. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6028-33. doi: 10.1073/pnas.1001796107. Epub 2010 Mar 15. Proc Natl Acad Sci U S A. 2010. PMID: 20231445 Free PMC article.

7

Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance.

Mauer J, Chaurasia B, Plum L, Quast T, Hampel B, Blüher M, Kolanus W, Kahn CR, Brüning JC. Mauer J, et al. Among authors: bruning jc. PLoS Genet. 2010 May 6;6(5):e1000938. doi: 10.1371/journal.pgen.1000938. PLoS Genet. 2010. PMID: 20463885 Free PMC article.

8

Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-kappaB activation in macrophages.

Chaurasia B, Mauer J, Koch L, Goldau J, Kock AS, Brüning JC. Chaurasia B, et al. Among authors: bruning jc. Mol Cell Biol. 2010 Sep;30(17):4354-66. doi: 10.1128/MCB.00069-10. Epub 2010 Jun 28. Mol Cell Biol. 2010. PMID: 20584979 Free PMC article.

9

Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action.

Wunderlich FT, Ströhle P, Könner AC, Gruber S, Tovar S, Brönneke HS, Juntti-Berggren L, Li LS, van Rooijen N, Libert C, Berggren PO, Brüning JC. Wunderlich FT, et al. Among authors: bruning jc. Cell Metab. 2010 Sep 8;12(3):237-49. doi: 10.1016/j.cmet.2010.06.011. Cell Metab. 2010. PMID: 20816090 Free article.

10

Novel roles for JNK1 in metabolism.

Belgardt BF, Mauer J, Brüning JC. Belgardt BF, et al. Among authors: bruning jc. Aging (Albany NY). 2010 Sep;2(9):621-6. doi: 10.18632/aging.100192. Aging (Albany NY). 2010. PMID: 20834068 Free PMC article.

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