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Interleukin-6 is a potential therapeutic target in interleukin-6 dependent, estrogen receptor-α-positive breast cancer.
Breast Cancer (Dove Med Press). 2016 Feb 3;8:13-27. doi: 10.2147/BCTT.S92414. eCollection 2016.
Breast Cancer (Dove Med Press). 2016.
PMID: 26893580
Free PMC article.
Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor.
Perera TPS, Jovcheva E, Mevellec L, Vialard J, De Lange D, Verhulst T, Paulussen C, Van De Ven K, King P, Freyne E, Rees DC, Squires M, Saxty G, Page M, Murray CW, Gilissen R, Ward G, Thompson NT, Newell DR, Cheng N, Xie L, Yang J, Platero SJ, Karkera JD, Moy C, Angibaud P, Laquerre S, Lorenzi MV.
Perera TPS, et al. Among authors: verhulst t.
Mol Cancer Ther. 2017 Jun;16(6):1010-1020. doi: 10.1158/1535-7163.MCT-16-0589. Epub 2017 Mar 24.
Mol Cancer Ther. 2017.
PMID: 28341788
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A translational model-based approach to inform the choice of the dose in phase 1 oncology trials: the case study of erdafitinib.
Tosca EM, Terranova N, Stuyckens K, Dosne AG, Perera T, Vialard J, King P, Verhulst T, Perez-Ruixo JJ, Magni P, Poggesi I.
Tosca EM, et al. Among authors: verhulst t.
Cancer Chemother Pharmacol. 2022 Jan;89(1):117-128. doi: 10.1007/s00280-021-04370-7. Epub 2021 Nov 17.
Cancer Chemother Pharmacol. 2022.
PMID: 34786600
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Discovery and Pharmacological Characterization of JNJ-64619178, a Novel Small-Molecule Inhibitor of PRMT5 with Potent Antitumor Activity.
Brehmer D, Beke L, Wu T, Millar HJ, Moy C, Sun W, Mannens G, Pande V, Boeckx A, van Heerde E, Nys T, Gustin EM, Verbist B, Zhou L, Fan Y, Bhargava V, Safabakhsh P, Vinken P, Verhulst T, Gilbert A, Rai S, Graubert TA, Pastore F, Fiore D, Gu J, Johnson A, Philippar U, Morschhäuser B, Walker D, De Lange D, Keersmaekers V, Viellevoye M, Diels G, Schepens W, Thuring JW, Meerpoel L, Packman K, Lorenzi MV, Laquerre S.
Brehmer D, et al. Among authors: verhulst t.
Mol Cancer Ther. 2021 Dec;20(12):2317-2328. doi: 10.1158/1535-7163.MCT-21-0367. Epub 2021 Sep 28.
Mol Cancer Ther. 2021.
PMID: 34583982
Free PMC article.
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Inhibition of histone deacetylases by chlamydocin induces apoptosis and proteasome-mediated degradation of survivin.
De Schepper S, Bruwiere H, Verhulst T, Steller U, Andries L, Wouters W, Janicot M, Arts J, Van Heusden J.
De Schepper S, et al. Among authors: verhulst t.
J Pharmacol Exp Ther. 2003 Feb;304(2):881-8. doi: 10.1124/jpet.102.042903.
J Pharmacol Exp Ther. 2003.
PMID: 12538846
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Automated beta galactosidase activity bioassay for adult Daphnia magna versus classic immobilization test.
Weltens R, Vanderplaetse F, Vangenechten C, Verhulst T.
Weltens R, et al. Among authors: verhulst t.
Bull Environ Contam Toxicol. 2000 Aug;65(2):139-46. doi: 10.1007/s0012800107.
Bull Environ Contam Toxicol. 2000.
PMID: 10885989
No abstract available.
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