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Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo.
Luke T, Wu H, Zhao J, Channappanavar R, Coleman CM, Jiao JA, Matsushita H, Liu Y, Postnikova EN, Ork BL, Glenn G, Flyer D, Defang G, Raviprakash K, Kochel T, Wang J, Nie W, Smith G, Hensley LE, Olinger GG, Kuhn JH, Holbrook MR, Johnson RF, Perlman S, Sullivan E, Frieman MB. Luke T, et al. Among authors: hensley le. Sci Transl Med. 2016 Feb 17;8(326):326ra21. doi: 10.1126/scitranslmed.aaf1061. Sci Transl Med. 2016. PMID: 26888429
Inhibition of heat-shock protein 90 reduces Ebola virus replication.
Smith DR, McCarthy S, Chrovian A, Olinger G, Stossel A, Geisbert TW, Hensley LE, Connor JH. Smith DR, et al. Among authors: hensley le. Antiviral Res. 2010 Aug;87(2):187-94. doi: 10.1016/j.antiviral.2010.04.015. Epub 2010 May 7. Antiviral Res. 2010. PMID: 20452380 Free PMC article.
Potential vaccines and post-exposure treatments for filovirus infections.
Friedrich BM, Trefry JC, Biggins JE, Hensley LE, Honko AN, Smith DR, Olinger GG. Friedrich BM, et al. Among authors: hensley le. Viruses. 2012 Sep;4(9):1619-50. doi: 10.3390/v4091619. Epub 2012 Sep 21. Viruses. 2012. PMID: 23170176 Free PMC article. Review.
Ebola virus genome plasticity as a marker of its passaging history: a comparison of in vitro passaging to non-human primate infection.
Kugelman JR, Lee MS, Rossi CA, McCarthy SE, Radoshitzky SR, Dye JM, Hensley LE, Honko A, Kuhn JH, Jahrling PB, Warren TK, Whitehouse CA, Bavari S, Palacios G. Kugelman JR, et al. Among authors: hensley le. PLoS One. 2012;7(11):e50316. doi: 10.1371/journal.pone.0050316. Epub 2012 Nov 28. PLoS One. 2012. PMID: 23209706 Free PMC article.
Pathology of experimental aerosol Zaire ebolavirus infection in rhesus macaques.
Twenhafel NA, Mattix ME, Johnson JC, Robinson CG, Pratt WD, Cashman KA, Wahl-Jensen V, Terry C, Olinger GG, Hensley LE, Honko AN. Twenhafel NA, et al. Among authors: hensley le. Vet Pathol. 2013 May;50(3):514-29. doi: 10.1177/0300985812469636. Epub 2012 Dec 23. Vet Pathol. 2013. PMID: 23262834
Aerosol exposure to Rift Valley fever virus causes earlier and more severe neuropathology in the murine model, which has important implications for therapeutic development.
Reed C, Lin K, Wilhelmsen C, Friedrich B, Nalca A, Keeney A, Donnelly G, Shamblin J, Hensley LE, Olinger G, Smith DR. Reed C, et al. Among authors: hensley le. PLoS Negl Trop Dis. 2013 Apr 4;7(4):e2156. doi: 10.1371/journal.pntd.0002156. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23593523 Free PMC article.
FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection.
Johansen LM, Brannan JM, Delos SE, Shoemaker CJ, Stossel A, Lear C, Hoffstrom BG, Dewald LE, Schornberg KL, Scully C, Lehár J, Hensley LE, White JM, Olinger GG. Johansen LM, et al. Among authors: hensley le. Sci Transl Med. 2013 Jun 19;5(190):190ra79. doi: 10.1126/scitranslmed.3005471. Sci Transl Med. 2013. PMID: 23785035 Free PMC article.
Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA.
Kuhn JH, Bào Y, Bavari S, Becker S, Bradfute S, Brauburger K, Rodney Brister J, Bukreyev AA, Caì Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, Formenty P, Freiberg AN, Hensley LE, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson KM, Klenk HD, Kobinger G, Lackemeyer MG, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. Kuhn JH, et al. Among authors: hensley le. Arch Virol. 2014 May;159(5):1229-37. doi: 10.1007/s00705-013-1877-2. Epub 2013 Nov 5. Arch Virol. 2014. PMID: 24190508 Free PMC article.
251 results