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The use of human neurons for novel drug discovery in dementia research.
Vargas-Caballero M, Willaime-Morawek S, Gomez-Nicola D, Perry VH, Bulters D, Mudher A. Vargas-Caballero M, et al. Among authors: mudher a. Expert Opin Drug Discov. 2016;11(4):355-67. doi: 10.1517/17460441.2016.1154528. Epub 2016 Mar 1. Expert Opin Drug Discov. 2016. PMID: 26878555 Review.
CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice.
Mancuso R, Fryatt G, Cleal M, Obst J, Pipi E, Monzón-Sandoval J, Ribe E, Winchester L, Webber C, Nevado A, Jacobs T, Austin N, Theunis C, Grauwen K, Daniela Ruiz E, Mudher A, Vicente-Rodriguez M, Parker CA, Simmons C, Cash D, Richardson J; NIMA Consortium; Jones DNC, Lovestone S, Gómez-Nicola D, Perry VH. Mancuso R, et al. Among authors: mudher a. Brain. 2019 Oct 1;142(10):3243-3264. doi: 10.1093/brain/awz241. Brain. 2019. PMID: 31504240 Free PMC article.
Drug repositioning for Alzheimer's disease.
Corbett A, Pickett J, Burns A, Corcoran J, Dunnett SB, Edison P, Hagan JJ, Holmes C, Jones E, Katona C, Kearns I, Kehoe P, Mudher A, Passmore A, Shepherd N, Walsh F, Ballard C. Corbett A, et al. Among authors: mudher a. Nat Rev Drug Discov. 2012 Nov;11(11):833-46. doi: 10.1038/nrd3869. Nat Rev Drug Discov. 2012. PMID: 23123941 Review.
Atypical, non-standard functions of the microtubule associated Tau protein.
Sotiropoulos I, Galas MC, Silva JM, Skoulakis E, Wegmann S, Maina MB, Blum D, Sayas CL, Mandelkow EM, Mandelkow E, Spillantini MG, Sousa N, Avila J, Medina M, Mudher A, Buee L. Sotiropoulos I, et al. Among authors: mudher a. Acta Neuropathol Commun. 2017 Nov 29;5(1):91. doi: 10.1186/s40478-017-0489-6. Acta Neuropathol Commun. 2017. PMID: 29187252 Free PMC article. Review.
55 results