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Mammalian Autophagy: How Does It Work?
Bento CF, Renna M, Ghislat G, Puri C, Ashkenazi A, Vicinanza M, Menzies FM, Rubinsztein DC. Bento CF, et al. Among authors: rubinsztein dc. Annu Rev Biochem. 2016 Jun 2;85:685-713. doi: 10.1146/annurev-biochem-060815-014556. Epub 2016 Feb 8. Annu Rev Biochem. 2016. PMID: 26865532 Review.
Rapamycin alleviates toxicity of different aggregate-prone proteins.
Berger Z, Ravikumar B, Menzies FM, Oroz LG, Underwood BR, Pangalos MN, Schmitt I, Wullner U, Evert BO, O'Kane CJ, Rubinsztein DC. Berger Z, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2006 Feb 1;15(3):433-42. doi: 10.1093/hmg/ddi458. Epub 2005 Dec 20. Hum Mol Genet. 2006. PMID: 16368705
Dyneins, autophagy, aggregation and neurodegeneration.
Rubinsztein DC, Ravikumar B, Acevedo-Arozena A, Imarisio S, O'Kane CJ, Brown SD. Rubinsztein DC, et al. Autophagy. 2005 Oct-Dec;1(3):177-8. doi: 10.4161/auto.1.3.2050. Epub 2005 Oct 21. Autophagy. 2005. PMID: 16874055 Review.
Potential therapeutic applications of autophagy.
Rubinsztein DC, Gestwicki JE, Murphy LO, Klionsky DJ. Rubinsztein DC, et al. Nat Rev Drug Discov. 2007 Apr;6(4):304-12. doi: 10.1038/nrd2272. Nat Rev Drug Discov. 2007. PMID: 17396135 Review.
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.
Sarkar S, Perlstein EO, Imarisio S, Pineau S, Cordenier A, Maglathlin RL, Webster JA, Lewis TA, O'Kane CJ, Schreiber SL, Rubinsztein DC. Sarkar S, et al. Among authors: rubinsztein dc. Nat Chem Biol. 2007 Jun;3(6):331-8. doi: 10.1038/nchembio883. Epub 2007 May 7. Nat Chem Biol. 2007. PMID: 17486044 Free PMC article.
444 results