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Tweaking Subtype Selectivity and Agonist Efficacy at (S)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) Receptors in a Small Series of BnTetAMPA Analogues.
Wang SY, Larsen Y, Navarrete CV, Jensen AA, Nielsen B, Al-Musaed A, Frydenvang K, Kastrup JS, Pickering DS, Clausen RP. Wang SY, et al. Among authors: frydenvang k. J Med Chem. 2016 Mar 10;59(5):2244-54. doi: 10.1021/acs.jmedchem.5b01982. Epub 2016 Feb 22. J Med Chem. 2016. PMID: 26862980
Selective inhibitors of glial GABA uptake: synthesis, absolute stereochemistry, and pharmacology of the enantiomers of 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole (exo-THPO) and analogues.
Falch E, Perregaard J, FrŁlund B, SŁkilde B, Buur A, Hansen LM, Frydenvang K, Brehm L, Bolvig T, Larsson OM, Sanchez C, White HS, Schousboe A, Krogsgaard-Larsen P. Falch E, et al. Among authors: frydenvang k. J Med Chem. 1999 Dec 30;42(26):5402-14. doi: 10.1021/jm9904452. J Med Chem. 1999. PMID: 10639282
Resolution, configurational assignment, and enantiopharmacology of 2-amino-3-[3-hydroxy-5-(2-methyl-2H- tetrazol-5-yl)isoxazol-4-yl]propionic acid, a potent GluR3- and GluR4-preferring AMPA receptor agonist.
Vogensen SB, Jensen HS, Stensbøl TB, Frydenvang K, Bang-Andersen B, Johansen TN, Egebjerg J, Krogsgaard-Larsen P. Vogensen SB, et al. Among authors: frydenvang k. Chirality. 2000 Nov;12(10):705-13. doi: 10.1002/1520-636X(2000)12:10<705::AID-CHIR2>3.0.CO;2-9. Chirality. 2000. PMID: 11054828
99 results