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The Emerging Importance of IgG Fab Glycosylation in Immunity.
van de Bovenkamp FS, Hafkenscheid L, Rispens T, Rombouts Y. van de Bovenkamp FS, et al. Among authors: hafkenscheid l. J Immunol. 2016 Feb 15;196(4):1435-41. doi: 10.4049/jimmunol.1502136. J Immunol. 2016. PMID: 26851295 Free article. Review.
Adaptive antibody diversification through N-linked glycosylation of the immunoglobulin variable region.
van de Bovenkamp FS, Derksen NIL, Ooijevaar-de Heer P, van Schie KA, Kruithof S, Berkowska MA, van der Schoot CE, IJspeert H, van der Burg M, Gils A, Hafkenscheid L, Toes REM, Rombouts Y, Plomp R, Wuhrer M, van Ham SM, Vidarsson G, Rispens T. van de Bovenkamp FS, et al. Among authors: hafkenscheid l. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1901-1906. doi: 10.1073/pnas.1711720115. Epub 2018 Feb 5. Proc Natl Acad Sci U S A. 2018. PMID: 29432186 Free PMC article.
B-cell receptor sequencing of anti-citrullinated protein antibody (ACPA) IgG-expressing B cells indicates a selective advantage for the introduction of N-glycosylation sites during somatic hypermutation.
Vergroesen RD, Slot LM, Hafkenscheid L, Koning MT, van der Voort EIH, Grooff CA, Zervakis G, Veelken H, Huizinga TWJ, Rispens T, Scherer HU, Toes REM. Vergroesen RD, et al. Among authors: hafkenscheid l. Ann Rheum Dis. 2018 Jun;77(6):956-958. doi: 10.1136/annrheumdis-2017-212052. Epub 2017 Aug 23. Ann Rheum Dis. 2018. PMID: 28835463 No abstract available.
Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation.
Kissel T, Ge C, Hafkenscheid L, Kwekkeboom JC, Slot LM, Cavallari M, He Y, van Schie KA, Vergroesen RD, Kampstra ASB, Reijm S, Stoeken-Rijsbergen G, Koeleman C, Voortman LM, Heitman LH, Xu B, Pruijn GJM, Wuhrer M, Rispens T, Huizinga TWJ, Scherer HU, Reth M, Holmdahl R, Toes REM. Kissel T, et al. Among authors: hafkenscheid l. Sci Adv. 2022 Feb 11;8(6):eabm1759. doi: 10.1126/sciadv.abm1759. Epub 2022 Feb 9. Sci Adv. 2022. PMID: 35138894 Free PMC article.
Role of N-Glycosylation in FcγRIIIa interaction with IgG.
Van Coillie J, Schulz MA, Bentlage AEH, de Haan N, Ye Z, Geerdes DM, van Esch WJE, Hafkenscheid L, Miller RL, Narimatsu Y, Vakhrushev SY, Yang Z, Vidarsson G, Clausen H. Van Coillie J, et al. Among authors: hafkenscheid l. Front Immunol. 2022 Sep 9;13:987151. doi: 10.3389/fimmu.2022.987151. eCollection 2022. Front Immunol. 2022. PMID: 36189205 Free PMC article.
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