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Nuclear compartmentalization of DNA repair.
Kalousi A, Soutoglou E. Kalousi A, et al. Curr Opin Genet Dev. 2016 Apr;37:148-157. doi: 10.1016/j.gde.2016.05.013. Epub 2016 Jun 5. Curr Opin Genet Dev. 2016. PMID: 27266837 Review.
A high-throughput chemical screen with FDA approved drugs reveals that the antihypertensive drug Spironolactone impairs cancer cell survival by inhibiting homology directed repair.
Shahar OD, Kalousi A, Eini L, Fisher B, Weiss A, Darr J, Mazina O, Bramson S, Kupiec M, Eden A, Meshorer E, Mazin AV, Brino L, Goldberg M, Soutoglou E. Shahar OD, et al. Among authors: kalousi a. Nucleic Acids Res. 2014 May;42(9):5689-701. doi: 10.1093/nar/gku217. Epub 2014 Mar 25. Nucleic Acids Res. 2014. PMID: 24682826 Free PMC article.
TIRR regulates 53BP1 by masking its histone methyl-lysine binding function.
Drané P, Brault ME, Cui G, Meghani K, Chaubey S, Detappe A, Parnandi N, He Y, Zheng XF, Botuyan MV, Kalousi A, Yewdell WT, Münch C, Harper JW, Chaudhuri J, Soutoglou E, Mer G, Chowdhury D. Drané P, et al. Among authors: kalousi a. Nature. 2017 Mar 9;543(7644):211-216. doi: 10.1038/nature21358. Epub 2017 Feb 27. Nature. 2017. PMID: 28241136 Free PMC article.
Minimized combinatorial CRISPR screens identify genetic interactions in autophagy.
Diehl V, Wegner M, Grumati P, Husnjak K, Schaubeck S, Gubas A, Shah VJ, Polat IH, Langschied F, Prieto-Garcia C, Müller K, Kalousi A, Ebersberger I, Brandts CH, Dikic I, Kaulich M. Diehl V, et al. Among authors: kalousi a. Nucleic Acids Res. 2021 Jun 4;49(10):5684-5704. doi: 10.1093/nar/gkab309. Nucleic Acids Res. 2021. PMID: 33956155 Free PMC article.
13 results