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Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics.
Kalinowski DS, Stefani C, Toyokuni S, Ganz T, Anderson GJ, Subramaniam NV, Trinder D, Olynyk JK, Chua A, Jansson PJ, Sahni S, Lane DJ, Merlot AM, Kovacevic Z, Huang ML, Lee CS, Richardson DR. Kalinowski DS, et al. Among authors: lane dj. Biochim Biophys Acta. 2016 Apr;1863(4):727-48. doi: 10.1016/j.bbamcr.2016.01.026. Epub 2016 Feb 2. Biochim Biophys Acta. 2016. PMID: 26844773 Free article. Review.
Lysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT).
Gutierrez EM, Seebacher NA, Arzuman L, Kovacevic Z, Lane DJ, Richardson V, Merlot AM, Lok H, Kalinowski DS, Sahni S, Jansson PJ, Richardson DR. Gutierrez EM, et al. Among authors: lane dj. Biochim Biophys Acta. 2016 Jul;1863(7 Pt A):1665-81. doi: 10.1016/j.bbamcr.2016.04.017. Epub 2016 Apr 19. Biochim Biophys Acta. 2016. PMID: 27102538 Free article.
Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes.
Lane DJR, Bae DH, Siafakas AR, Suryo Rahmanto Y, Al-Akra L, Jansson PJ, Casero RA Jr, Richardson DR. Lane DJR, et al. Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2793-2813. doi: 10.1016/j.bbadis.2018.05.007. Epub 2018 May 16. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29777905 Free PMC article.
The old and new biochemistry of polyamines.
Bae DH, Lane DJR, Jansson PJ, Richardson DR. Bae DH, et al. Biochim Biophys Acta Gen Subj. 2018 Sep;1862(9):2053-2068. doi: 10.1016/j.bbagen.2018.06.004. Epub 2018 Jun 8. Biochim Biophys Acta Gen Subj. 2018. PMID: 29890242 Review.
199 results