Chen Y - Search Results

1

Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats.

Liu L, Miao MX, Zhong ZY, Xu P, Chen Y, Liu XD. Liu L, et al. Among authors: chen y. Acta Pharmacol Sin. 2016 Apr;37(4):561-70. doi: 10.1038/aps.2015.160. Epub 2016 Feb 1. Acta Pharmacol Sin. 2016. PMID: 26838075 Free PMC article.

2

Characteristics of β-oxidative and reductive metabolism on the acyl side chain of cinnamic acid and its analogues in rats.

Zhao KJ, Chen Y, Hong SJ, Yang YT, Xu J, Yang HY, Zhu L, Liu M, Xie QS, Tang XG, Yang TT, Zhou YQ, Liu L, Liu XD. Zhao KJ, et al. Among authors: chen y. Acta Pharmacol Sin. 2019 Aug;40(8):1106-1118. doi: 10.1038/s41401-019-0218-8. Epub 2019 Feb 21. Acta Pharmacol Sin. 2019. PMID: 30792487 Free PMC article.

3

Physiologically based pharmacokinetic-pharmacodynamic modeling for prediction of vonoprazan pharmacokinetics and its inhibition on gastric acid secretion following intravenous/oral administration to rats, dogs and humans.

Kong WM, Sun BB, Wang ZJ, Zheng XK, Zhao KJ, Chen Y, Zhang JX, Liu PH, Zhu L, Xu RJ, Li P, Liu L, Liu XD. Kong WM, et al. Among authors: chen y. Acta Pharmacol Sin. 2020 Jun;41(6):852-865. doi: 10.1038/s41401-019-0353-2. Epub 2020 Jan 22. Acta Pharmacol Sin. 2020. PMID: 31969689 Free PMC article.

4

Unconjugated bilirubin elevation impairs the function and expression of breast cancer resistance protein (BCRP) at the blood-brain barrier in bile duct-ligated rats.

Xu P, Ling ZL, Zhang J, Li Y, Shu N, Zhong ZY, Chen Y, Di XY, Wang ZJ, Liu L, Liu XD. Xu P, et al. Among authors: chen y. Acta Pharmacol Sin. 2016 Aug;37(8):1129-40. doi: 10.1038/aps.2016.25. Epub 2016 May 16. Acta Pharmacol Sin. 2016. PMID: 27180978 Free PMC article.

5

Ciprofloxacin blocked enterohepatic circulation of diclofenac and alleviated NSAID-induced enteropathy in rats partly by inhibiting intestinal β-glucuronidase activity.

Zhong ZY, Sun BB, Shu N, Xie QS, Tang XG, Ling ZL, Wang F, Zhao KJ, Xu P, Zhang M, Li Y, Chen Y, Liu L, Xia LZ, Liu XD. Zhong ZY, et al. Among authors: chen y. Acta Pharmacol Sin. 2016 Jul;37(7):1002-12. doi: 10.1038/aps.2016.54. Epub 2016 May 16. Acta Pharmacol Sin. 2016. PMID: 27180979 Free PMC article.

6

Acute liver failure enhances oral plasma exposure of zidovudine in rats by downregulation of hepatic UGT2B7 and intestinal P-gp.

Wang F, Miao MX, Sun BB, Wang ZJ, Tang XG, Chen Y, Zhao KJ, Liu XD, Liu L. Wang F, et al. Among authors: chen y. Acta Pharmacol Sin. 2017 Nov;38(11):1554-1565. doi: 10.1038/aps.2017.54. Epub 2017 Aug 3. Acta Pharmacol Sin. 2017. PMID: 28770824 Free PMC article.

7

Altered Function and Expression of ABC Transporters at the Blood-Brain Barrier and Increased Brain Distribution of Phenobarbital in Acute Liver Failure Mice.

Liu L, Miao M, Chen Y, Wang Z, Sun B, Liu X. Liu L, et al. Among authors: chen y. Front Pharmacol. 2018 Mar 6;9:190. doi: 10.3389/fphar.2018.00190. eCollection 2018. Front Pharmacol. 2018. PMID: 29559914 Free PMC article.

8

Simultaneously predict pharmacokinetic interaction of rifampicin with oral versus intravenous substrates of cytochrome P450 3A/P‑glycoprotein to healthy human using a semi-physiologically based pharmacokinetic model involving both enzyme and transporter turnover.

Qian CQ, Zhao KJ, Chen Y, Liu L, Liu XD. Qian CQ, et al. Among authors: chen y. Eur J Pharm Sci. 2019 Jun 15;134:194-204. doi: 10.1016/j.ejps.2019.04.026. Epub 2019 Apr 29. Eur J Pharm Sci. 2019. PMID: 31047967

9

Short-chain fatty acids oppositely altered expressions and functions of intestinal cytochrome P4503A and P-glycoprotein and affected pharmacokinetics of verapamil following oral administration to rats.

Zhang J, Xie Q, Kong W, Wang Z, Wang S, Zhao K, Chen Y, Liu X, Liu L. Zhang J, et al. Among authors: chen y. J Pharm Pharmacol. 2020 Mar;72(3):448-460. doi: 10.1111/jphp.13215. Epub 2019 Dec 20. J Pharm Pharmacol. 2020. PMID: 31863502

10

Aggravation of clozapine-induced hepatotoxicity by glycyrrhetinic acid in rats.

Jia LL, Zhong ZY, Li F, Ling ZL, Chen Y, Zhao WM, Li Y, Jiang SW, Xu P, Yang Y, Hu MY, Liu L, Liu XD. Jia LL, et al. Among authors: chen y. J Pharmacol Sci. 2014;124(4):468-79. doi: 10.1254/jphs.13257fp. J Pharmacol Sci. 2014. PMID: 24739264 Free article.

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