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Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2.
Ware JJ, Chen X, Vink J, Loukola A, Minica C, Pool R, Milaneschi Y, Mangino M, Menni C, Chen J, Peterson RE, Auro K, Lyytikäinen LP, Wedenoja J, Stiby AI, Hemani G, Willemsen G, Hottenga JJ, Korhonen T, Heliövaara M, Perola M, Rose RJ, Paternoster L, Timpson N, Wassenaar CA, Zhu AZ, Davey Smith G, Raitakari OT, Lehtimäki T, Kähönen M, Koskinen S, Spector T, Penninx BW, Salomaa V, Boomsma DI, Tyndale RF, Kaprio J, Munafò MR. Ware JJ, et al. Among authors: tyndale rf. Sci Rep. 2016 Feb 1;6:20092. doi: 10.1038/srep20092. Sci Rep. 2016. PMID: 26833182 Free PMC article.
Breaking barriers in the genomics and pharmacogenetics of drug addiction.
Ho MK, Goldman D, Heinz A, Kaprio J, Kreek MJ, Li MD, Munafò MR, Tyndale RF. Ho MK, et al. Among authors: tyndale rf. Clin Pharmacol Ther. 2010 Dec;88(6):779-91. doi: 10.1038/clpt.2010.175. Epub 2010 Oct 27. Clin Pharmacol Ther. 2010. PMID: 20981002 Free PMC article. Review.
Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation.
Zhu AZ, Binnington MJ, Renner CC, Lanier AP, Hatsukami DK, Stepanov I, Watson CH, Sosnoff CS, Benowitz NL, Tyndale RF. Zhu AZ, et al. Among authors: tyndale rf. Carcinogenesis. 2013 Jan;34(1):93-101. doi: 10.1093/carcin/bgs306. Epub 2012 Oct 1. Carcinogenesis. 2013. PMID: 23027621 Free PMC article.
The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex.
Zhu AZ, Renner CC, Hatsukami DK, Swan GE, Lerman C, Benowitz NL, Tyndale RF. Zhu AZ, et al. Among authors: tyndale rf. Cancer Epidemiol Biomarkers Prev. 2013 Apr;22(4):708-18. doi: 10.1158/1055-9965.EPI-12-1234-T. Epub 2013 Jan 31. Cancer Epidemiol Biomarkers Prev. 2013. PMID: 23371292 Free PMC article.
441 results