Oakley F - Search Results

1

Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease.

Fox C, Cocchiaro P, Oakley F, Howarth R, Callaghan K, Leslie J, Luli S, Wood KM, Genovese F, Sheerin NS, Moles A. Fox C, et al. Among authors: oakley f. Sci Rep. 2016 Feb 2;6:20101. doi: 10.1038/srep20101. Sci Rep. 2016. PMID: 26831567 Free PMC article.

2

Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.

Ebrahimkhani MR, Oakley F, Murphy LB, Mann J, Moles A, Perugorria MJ, Ellis E, Lakey AF, Burt AD, Douglass A, Wright MC, White SA, Jaffré F, Maroteaux L, Mann DA. Ebrahimkhani MR, et al. Among authors: oakley f. Nat Med. 2011 Nov 27;17(12):1668-73. doi: 10.1038/nm.2490. Nat Med. 2011. PMID: 22120177 Free PMC article.

3

The NF-κB subunit c-Rel stimulates cardiac hypertrophy and fibrosis.

Gaspar-Pereira S, Fullard N, Townsend PA, Banks PS, Ellis EL, Fox C, Maxwell AG, Murphy LB, Kirk A, Bauer R, Caamaño JH, Figg N, Foo RS, Mann J, Mann DA, Oakley F. Gaspar-Pereira S, et al. Among authors: oakley f. Am J Pathol. 2012 Mar;180(3):929-939. doi: 10.1016/j.ajpath.2011.11.007. Epub 2011 Dec 30. Am J Pathol. 2012. PMID: 22210479 Free PMC article.

4

Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans.

Pritchett J, Harvey E, Athwal V, Berry A, Rowe C, Oakley F, Moles A, Mann DA, Bobola N, Sharrocks AD, Thomson BJ, Zaitoun AM, Irving WL, Guha IN, Hanley NA, Hanley KP. Pritchett J, et al. Among authors: oakley f. Hepatology. 2012 Sep;56(3):1108-16. doi: 10.1002/hep.25758. Hepatology. 2012. PMID: 22488688 Free PMC article.

5

Multigenerational epigenetic adaptation of the hepatic wound-healing response.

Zeybel M, Hardy T, Wong YK, Mathers JC, Fox CR, Gackowska A, Oakley F, Burt AD, Wilson CL, Anstee QM, Barter MJ, Masson S, Elsharkawy AM, Mann DA, Mann J. Zeybel M, et al. Among authors: oakley f. Nat Med. 2012 Sep;18(9):1369-77. doi: 10.1038/nm.2893. Nat Med. 2012. PMID: 22941276 Free PMC article.

6

Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response.

Moles A, Sanchez AM, Banks PS, Murphy LB, Luli S, Borthwick L, Fisher A, O'Reilly S, van Laar JM, White SA, Perkins ND, Burt AD, Mann DA, Oakley F. Moles A, et al. Among authors: oakley f. Hepatology. 2013 Feb;57(2):817-28. doi: 10.1002/hep.26068. Epub 2013 Jan 8. Hepatology. 2013. PMID: 22996371 Free PMC article.

7

The c-Rel subunit of NF-κB regulates epidermal homeostasis and promotes skin fibrosis in mice.

Fullard N, Moles A, O'Reilly S, van Laar JM, Faini D, Diboll J, Reynolds NJ, Mann DA, Reichelt J, Oakley F. Fullard N, et al. Among authors: oakley f. Am J Pathol. 2013 Jun;182(6):2109-20. doi: 10.1016/j.ajpath.2013.02.016. Epub 2013 Apr 4. Am J Pathol. 2013. PMID: 23562440 Free PMC article.

8

A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse.

Moles A, Murphy L, Wilson CL, Chakraborty JB, Fox C, Park EJ, Mann J, Oakley F, Howarth R, Brain J, Masson S, Karin M, Seki E, Mann DA. Moles A, et al. Among authors: oakley f. J Hepatol. 2014 Apr;60(4):782-91. doi: 10.1016/j.jhep.2013.12.005. Epub 2013 Dec 11. J Hepatol. 2014. PMID: 24333183 Free PMC article.

9

NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma.

Wilson CL, Jurk D, Fullard N, Banks P, Page A, Luli S, Elsharkawy AM, Gieling RG, Chakraborty JB, Fox C, Richardson C, Callaghan K, Blair GE, Fox N, Lagnado A, Passos JF, Moore AJ, Smith GR, Tiniakos DG, Mann J, Oakley F, Mann DA. Wilson CL, et al. Among authors: oakley f. Nat Commun. 2015 Apr 16;6:6818. doi: 10.1038/ncomms7818. Nat Commun. 2015. PMID: 25879839 Free PMC article.

10

Ubiquitin C-terminal hydrolase 1: A novel functional marker for liver myofibroblasts and a therapeutic target in chronic liver disease.

Wilson CL, Murphy LB, Leslie J, Kendrick S, French J, Fox CR, Sheerin NS, Fisher A, Robinson JH, Tiniakos DG, Gray DA, Oakley F, Mann DA. Wilson CL, et al. Among authors: oakley f. J Hepatol. 2015 Dec;63(6):1421-8. doi: 10.1016/j.jhep.2015.07.034. Epub 2015 Aug 8. J Hepatol. 2015. PMID: 26264933 Free PMC article.

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