Moles A - Search Results

1

Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease.

Fox C, Cocchiaro P, Oakley F, Howarth R, Callaghan K, Leslie J, Luli S, Wood KM, Genovese F, Sheerin NS, Moles A. Fox C, et al. Among authors: moles a. Sci Rep. 2016 Feb 2;6:20101. doi: 10.1038/srep20101. Sci Rep. 2016. PMID: 26831567 Free PMC article.

2

Lysosomal protease cathepsin D; a new driver of apoptosis during acute kidney injury.

Cocchiaro P, Fox C, Tregidgo NW, Howarth R, Wood KM, Situmorang GR, Pavone LM, Sheerin NS, Moles A. Cocchiaro P, et al. Among authors: moles a. Sci Rep. 2016 Jun 7;6:27112. doi: 10.1038/srep27112. Sci Rep. 2016. PMID: 27271556 Free PMC article.

3

Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response.

Moles A, Sanchez AM, Banks PS, Murphy LB, Luli S, Borthwick L, Fisher A, O'Reilly S, van Laar JM, White SA, Perkins ND, Burt AD, Mann DA, Oakley F. Moles A, et al. Hepatology. 2013 Feb;57(2):817-28. doi: 10.1002/hep.26068. Epub 2013 Jan 8. Hepatology. 2013. PMID: 22996371 Free PMC article.

4

The NF-κB1 is a key regulator of acute but not chronic renal injury.

Fearn A, Situmorang GR, Fox C, Oakley F, Howarth R, Wilson CL, Kiosia A, Robson MG, Mann DA, Moles A, Sheerin NS. Fearn A, et al. Among authors: moles a. Cell Death Dis. 2017 Jun 15;8(6):e2883. doi: 10.1038/cddis.2017.233. Cell Death Dis. 2017. PMID: 28617440 Free PMC article.

5

The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease.

Cocchiaro P, De Pasquale V, Della Morte R, Tafuri S, Avallone L, Pizard A, Moles A, Pavone LM. Cocchiaro P, et al. Among authors: moles a. Front Cell Dev Biol. 2017 Dec 19;5:114. doi: 10.3389/fcell.2017.00114. eCollection 2017. Front Cell Dev Biol. 2017. PMID: 29312937 Free PMC article. Review.

6

Heparan sulfate in chronic kidney diseases: Exploring the role of 3-O-sulfation.

Ferreras L, Moles A, Situmorang GR, El Masri R, Wilson IL, Cooke K, Thompson E, Kusche-Gullberg M, Vivès RR, Sheerin NS, Ali S. Ferreras L, et al. Among authors: moles a. Biochim Biophys Acta Gen Subj. 2019 May;1863(5):839-848. doi: 10.1016/j.bbagen.2019.02.009. Epub 2019 Feb 19. Biochim Biophys Acta Gen Subj. 2019. PMID: 30794825 Free article.

7

A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse.

Moles A, Murphy L, Wilson CL, Chakraborty JB, Fox C, Park EJ, Mann J, Oakley F, Howarth R, Brain J, Masson S, Karin M, Seki E, Mann DA. Moles A, et al. J Hepatol. 2014 Apr;60(4):782-91. doi: 10.1016/j.jhep.2013.12.005. Epub 2013 Dec 11. J Hepatol. 2014. PMID: 24333183 Free PMC article.

8

Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.

Ebrahimkhani MR, Oakley F, Murphy LB, Mann J, Moles A, Perugorria MJ, Ellis E, Lakey AF, Burt AD, Douglass A, Wright MC, White SA, Jaffré F, Maroteaux L, Mann DA. Ebrahimkhani MR, et al. Among authors: moles a. Nat Med. 2011 Nov 27;17(12):1668-73. doi: 10.1038/nm.2490. Nat Med. 2011. PMID: 22120177 Free PMC article.

9

A RelA(p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB-dependent liver regeneration and cancer.

Moles A, Butterworth JA, Sanchez A, Hunter JE, Leslie J, Sellier H, Tiniakos D, Cockell SJ, Mann DA, Oakley F, Perkins ND. Moles A, et al. Oncogene. 2016 Sep 1;35(35):4623-32. doi: 10.1038/onc.2015.526. Epub 2016 Feb 8. Oncogene. 2016. PMID: 26853469 Free PMC article.

10

The c-Rel subunit of NF-κB regulates epidermal homeostasis and promotes skin fibrosis in mice.

Fullard N, Moles A, O'Reilly S, van Laar JM, Faini D, Diboll J, Reynolds NJ, Mann DA, Reichelt J, Oakley F. Fullard N, et al. Among authors: moles a. Am J Pathol. 2013 Jun;182(6):2109-20. doi: 10.1016/j.ajpath.2013.02.016. Epub 2013 Apr 4. Am J Pathol. 2013. PMID: 23562440 Free PMC article.

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