Peräkylä M - Search Results

1

The Effects of Sequence Variation on Genome-wide NRF2 Binding--New Target Genes and Regulatory SNPs.

Kuosmanen SM, Viitala S, Laitinen T, Peräkylä M, Pölönen P, Kansanen E, Leinonen H, Raju S, Wienecke-Baldacchino A, Närvänen A, Poso A, Heinäniemi M, Heikkinen S, Levonen AL. Kuosmanen SM, et al. Among authors: perakyla m. Nucleic Acids Res. 2016 Feb 29;44(4):1760-75. doi: 10.1093/nar/gkw052. Epub 2016 Jan 29. Nucleic Acids Res. 2016. PMID: 26826707 Free PMC article.

2

Free energy simulations and MM-PBSA analyses on the affinity and specificity of steroid binding to antiestradiol antibody.

Laitinen T, Kankare JA, Peräkylä M. Laitinen T, et al. Among authors: perakyla m. Proteins. 2004 Apr 1;55(1):34-43. doi: 10.1002/prot.10399. Proteins. 2004. PMID: 14997538

3

MM-PBSA free energy analysis of endo-1,4-xylanase II (XynII)-substrate complexes: binding of the reactive sugar in a skew boat and chair conformation.

Laitinen T, Rouvinen J, Peräkylä M. Laitinen T, et al. Among authors: perakyla m. Org Biomol Chem. 2003 Oct 21;1(20):3535-40. doi: 10.1039/b307335a. Org Biomol Chem. 2003. PMID: 14599014

4

Inversion of the roles of the nucleophile and acid/base catalysts in the covalent binding of epoxyalkyl xyloside inhibitor to the catalytic glutamates of endo-1,4-beta-xylanase (XYNII): a molecular dynamics study.

Laitinen T, Rouvinen J, Peräkylä M. Laitinen T, et al. Among authors: perakyla m. Protein Eng. 2000 Apr;13(4):247-52. doi: 10.1093/protein/13.4.247. Protein Eng. 2000. PMID: 10810155

5

Amino acids important for ligand specificity of the human constitutive androstane receptor.

Jyrkkärinne J, Windshügel B, Mäkinen J, Ylisirniö M, Peräkylä M, Poso A, Sippl W, Honkakoski P. Jyrkkärinne J, et al. Among authors: perakyla m. J Biol Chem. 2005 Feb 18;280(7):5960-71. doi: 10.1074/jbc.M411241200. Epub 2004 Nov 29. J Biol Chem. 2005. PMID: 15572376 Free article.

6

Evaluation of the antiviral efficacy of bis[1,2]dithiolo[1,4]thiazines and bis[1,2]dithiolopyrrole derivatives against the nucelocapsid protein of the Feline Immunodeficiency Virus (FIV) as a model for HIV infection.

Asquith CR, Meli ML, Konstantinova LS, Laitinen T, Peräkylä M, Poso A, Rakitin OA, Allenspach K, Hofmann-Lehmann R, Hilton ST. Asquith CR, et al. Among authors: perakyla m. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2640-4. doi: 10.1016/j.bmcl.2014.04.073. Epub 2014 Apr 26. Bioorg Med Chem Lett. 2014. PMID: 24813732

7

Identification of novel peptide inhibitors for human trypsins.

Wu P, Weisell J, Pakkala M, Peräkylä M, Zhu L, Koistinen R, Koivunen E, Stenman UH, Närvänen A, Koistinen H. Wu P, et al. Among authors: perakyla m. Biol Chem. 2010 Feb-Mar;391(2-3):283-293. doi: 10.1515/bc.2010.030. Biol Chem. 2010. PMID: 20128688

8

Conformational and biochemical analysis of the cyclic peptides which modulate serine protease activity.

Pakkala M, Jylhäsalmi A, Wu P, Leinonen J, Stenman UH, Santa H, Vepsäläinen J, Peräkylä M, Närvänen A. Pakkala M, et al. Among authors: perakyla m. J Pept Sci. 2004 Jul;10(7):439-47. doi: 10.1002/psc.557. J Pept Sci. 2004. PMID: 15298179

9

Preclinical pharmacology of FL442, a novel nonsteroidal androgen receptor modulator.

Poutiainen PK, Huhtala T, Jääskeläinen T, Petsalo A, Küblbeck J, Kaikkonen S, Palvimo JJ, Raunio H, Närvänen A, Peräkylä M, Juvonen RO, Honkakoski P, Laatikainen R, Pulkkinen JT. Poutiainen PK, et al. Among authors: perakyla m. Mol Cell Endocrinol. 2014 Apr 25;387(1-2):8-18. doi: 10.1016/j.mce.2014.02.008. Epub 2014 Feb 22. Mol Cell Endocrinol. 2014. PMID: 24565895

10

Overexpression of SUMO perturbs the growth and development of Caenorhabditis elegans.

Rytinki MM, Lakso M, Pehkonen P, Aarnio V, Reisner K, Peräkylä M, Wong G, Palvimo JJ. Rytinki MM, et al. Among authors: perakyla m. Cell Mol Life Sci. 2011 Oct;68(19):3219-32. doi: 10.1007/s00018-011-0627-4. Epub 2011 Jan 21. Cell Mol Life Sci. 2011. PMID: 21253676 Free PMC article.

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