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From preclinical development to clinical application: Kit formulation for radiolabelling the minigastrin analogue CP04 with In-111 for a first-in-human clinical trial.
Pawlak D, Rangger C, Kolenc Peitl P, Garnuszek P, Maurin M, Ihli L, Kroselj M, Maina T, Maecke H, Erba P, Kremser L, Hubalewska-Dydejczyk A, Mikołajczak R, Decristoforo C. Pawlak D, et al. Among authors: maina t. Eur J Pharm Sci. 2016 Mar 31;85:1-9. doi: 10.1016/j.ejps.2016.01.023. Epub 2016 Jan 27. Eur J Pharm Sci. 2016. PMID: 26826279 Free PMC article.
Preclinical pharmacokinetics, biodistribution, radiation dosimetry and toxicity studies required for regulatory approval of a phase I clinical trial with (111)In-CP04 in medullary thyroid carcinoma patients.
Maina T, Konijnenberg MW, KolencPeitl P, Garnuszek P, Nock BA, Kaloudi A, Kroselj M, Zaletel K, Maecke H, Mansi R, Erba P, von Guggenberg E, Hubalewska-Dydejczyk A, Mikolajczak R, Decristoforo C. Maina T, et al. Eur J Pharm Sci. 2016 Aug 25;91:236-42. doi: 10.1016/j.ejps.2016.05.011. Epub 2016 May 14. Eur J Pharm Sci. 2016. PMID: 27185299 Free PMC article.
[111In]In-CP04 as a novel cholecystokinin-2 receptor ligand with theranostic potential in patients with progressive or metastatic medullary thyroid cancer: final results of a GRAN-T-MTC Phase I clinical trial.
Lezaic L, Erba PA, Decristoforo C, Zaletel K, Mikolajczak R, Maecke H, Maina T, Konijnenberg M, Kolenc P, Trofimiuk-Müldner M, Przybylik-Mazurek E, Virgolini I, de Jong M, Fröberg AC, Rangger C, Di Santo G, Skorkiewicz K, Garnuszek P, Solnica B, Nock BA, Fedak D, Gaweda P, Hubalewska-Dydejczyk A. Lezaic L, et al. Among authors: maina t. Eur J Nucl Med Mol Imaging. 2023 Feb;50(3):892-907. doi: 10.1007/s00259-022-05992-6. Epub 2022 Nov 5. Eur J Nucl Med Mol Imaging. 2023. PMID: 36334104 Free PMC article. Clinical Trial.
134 results