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Discovery of 7-Azanorbornane-Based Dual Agonists for the Delta and Kappa Opioid Receptors through an In Situ Screening Protocol.
Karaki F, Takamori T, Kawakami K, Sakurai S, Hidaka K, Ishii K, Oki T, Sato N, Atsumi N, Ashizawa K, Taguchi A, Ura A, Naruse T, Hirayama S, Nonaka M, Miyano K, Uezono Y, Fujii H. Karaki F, et al. Among authors: miyano k. Molecules. 2023 Oct 3;28(19):6925. doi: 10.3390/molecules28196925. Molecules. 2023. PMID: 37836768 Free PMC article.
Infusions of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produce antidepressant-like effects on learned helplessness rats through BDNF-TrkB signaling and AMPA receptor activation, and strengthen learning ability.
Shirayama Y, Iwata M, Miyano K, Hirose Y, Oda Y, Fujita Y, Hashimoto K. Shirayama Y, et al. Among authors: miyano k. Brain Res. 2023 Dec 15;1821:148567. doi: 10.1016/j.brainres.2023.148567. Epub 2023 Sep 7. Brain Res. 2023. PMID: 37689333
299 results