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SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells.
Xu SW, Law BYK, Qu SLQ, Hamdoun S, Chen J, Zhang W, Guo JR, Wu AG, Mok SWF, Zhang DW, Xia C, Sugimoto Y, Efferth T, Liu L, Wong VKW. Xu SW, et al. Among authors: liu l. Pharmacol Res. 2020 Mar;153:104660. doi: 10.1016/j.phrs.2020.104660. Epub 2020 Jan 23. Pharmacol Res. 2020. PMID: 31982489
Mutation of cysteine 46 in IKK-beta increases inflammatory responses.
Li T, Wong VK, Jiang ZH, Jiang SP, Liu Y, Wang TY, Yao XJ, Su XH, Yan FG, Liu J, Leung EL, Yi XQ, Wong YF, Zhou H, Liu L. Li T, et al. Among authors: liu j, liu y, liu l. Oncotarget. 2015 Oct 13;6(31):31805-19. doi: 10.18632/oncotarget.5567. Oncotarget. 2015. PMID: 26378659 Free PMC article.
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